Abstract: Systems, methods and devices are provided for the non-invasive behavioural monitoring of rodents within a rodent cage via the detection of interactions with a cage lid. A cage lid interaction sensor, positioned in close proximity to the cage lid, is employed to sense interactions with the cage lid. The resulting signals may be processed to determine a health status of the rodent. In some example embodiments, a lid sensing module is provided in that is configured for attachment to an existing rodent cage, permitting the insertion of the rodent cage into a cage rack after installation of the sensing module. In other example embodiments, a replacement cage lid is provided having an integrated lid interaction sensor and associated detection circuitry. Various example lid sensing modalities and associated sensor configurations are disclosed.