Abstract: Thermoresponsive skin barrier assemblies are disclosed. One such wound treatment assembly includes a pump configured to expel a biosealant to a pump output port when subjected to a thermal stimulus, and an adhesive substrate layer for covering the wound. The adhesive substrate layer includes a conduit configured to transport the biosealant from the output port to the wound. The assembly further includes a control module in signal communication with a wound leakage sensor configured to activate a heating element disposed in proximity to the pump when wound leakage is detected.

Abstract: A method for determining healing progress of a tissue disease state includes receiving a thermal image of a target wound area from a thermal imaging system, processing the thermal image to construct an isotherm map of at least one selected area, determining a thermal index value from the isotherm map, correlating the wound thermal index value with a reference thermal index value representative of an injury-free state.

Abstract: A method for assessing and reversing exercise impairment in adults having peripheral vascular disease includes quantifying a musculoskeletal deoxygenation level (MDL) of a human subject provided by a wearable near infrared spectroscopy system configured to measure the deoxygenation level during exercise, comparing the quantified MDL to a range of pre-determined healthy MDL values for the subject, and, if the quantified MDL is outside of the pre-determined target MDL values, determining a corrective exercise intensity level or ‘dose’ effective to bring the MDL of the subject within the target MDL values and reverse the exercise impairment.

Abstract: A system for predicting an occurrence of a foot ulcer includes a mat configured to be stood upon by a human subject, a plurality of sensor arrays disposed on or in said mat and arranged in adjacent proximity to one another. Each sensor includes an oxygenation probe, itself including a first light source and a light detector, and a secondary probe operable to utilize the light detector of the oxygenation probe and itself including a plurality of light sources exclusive of the first light source. The plurality of light sources of the secondary probe are arranged in a pattern around the oxygenation probe. The oxygenation probe is located at the approximate geometric center of the pattern. The system further includes a control module in signal communication with the light detector, and configured to independently control emission of light from the first light source of the oxygenation probe and the plurality of light sources of the secondary probe.

Abstract: A method for determining healing progress of a tissue disease state includes receiving a thermal image of a target wound area from a thermal imaging system, processing the thermal image to construct an isotherm map of at least one selected area, determining a thermal index value from the isotherm map, correlating the wound thermal index value with a reference thermal index value representative of an injury-free state.

Abstract: A Wound Moisture and Assessment System includes a flexible coupon containing one or more electrochemical moisture sensors for measuring a moisture profile of a wound. The coupon is activated by a wireless RF scanner that provides power to the coupon for taking moisture measurements, receives the moisture measurements therefrom, and transmits the measurements to a computing device. The moisture measurements can be represented as a wound moisture map that allows a patient or caregiver to assess the health and healing progress of a wound such as an ulcer.

Abstract: Thermoresponsive skin barrier assemblies are disclosed. One such wound treatment assembly includes a pump configured to expel a biosealant to a pump output port when subjected to a thermal stimulus, and an adhesive substrate layer for covering the wound. The adhesive substrate layer includes a conduit configured to transport the biosealant from the output port to the wound. The assembly further includes a control module in signal communication with a wound leakage sensor configured to activate a heating element disposed in proximity to the pump when wound leakage is detected.

Abstract: Thermoresponsive skin barrier assemblies are disclosed. One such wound treatment assembly includes a pump configured to expel a biosealant to a pump output port when subjected to a thermal stimulus, and an adhesive substrate layer for covering the wound. The adhesive substrate layer includes a conduit configured to transport the biosealant from the output port to the wound. The assembly further includes a control module in signal communication with a wound leakage sensor configured to activate a heating element disposed in proximity to the pump when wound leakage is detected.

Abstract: Thermoresponsive skin barrier assemblies are disclosed. One such wound treatment assembly includes a pump configured to expel a biosealant to a pump output port when subjected to a thermal stimulus, and an adhesive substrate layer for covering the wound. The adhesive substrate layer includes a conduit configured to transport the biosealant from the output port to the wound. The assembly further includes a control module in signal communication with a wound leakage sensor configured to activate a heating element disposed in proximity to the pump when wound leakage is detected.

Abstract: A method and apparatus using ultrasonic sensors for determination of the pointing vector described by two points separated in space in the coordinate frame of the measuring system. For measurement, acoustic signals are transmitted from two emitters whose spatially separated coordinates form the desired pointing vector. Three detectors, associated receiver electronics and software are required to compute six distinct spheres from the time of flight measurements. The intersection of the three spheres, associated with each emitter, describe the desired location in the detector coordinate system of that emitter. With the coordinates of each emitter, the pointing vector is computed using standard geometry. A reference is required to determine the time of flight of the signals to each detector. Another embodiment uses an active reflective technique, where the timing is obtained through round trip transmission and reception of the signal with a known fixed delay at the vector points.

Abstract: A contactless precision, optical distance and angle measurement method and system optically measuring the position of a moveable object, the bending of the object, the torque applied to the object and the object's rotational velocity. The present invention includes a plurality of optical sensors placed around and adjacent to the moveable object which transmit optical signals to a surface of the object and receives the optic signals when predefined marker means are sensed. The received optic signals are then processed by non-linear estimation techniques known to those of skill in the art to obtain the desired information.

Abstract: A method and apparatus using ultrasonic sensors for determination of the pointing vector described by two points separated in space in the coordinate frame of the measuring system. For measurement, acoustic signals are transmitted from two emitters whose spatially separated coordinates form the desired pointing vector. Three detectors, associated receiver electronics and software are required to compute six distinct spheres from the time of flight measurements. The intersection of the three spheres, associated with each emitter, describe the desired location in the detector coordinate system of that emitter. With the coordinates of each emitter, the pointing vector is computed using standard geometry. A reference is required to determine the time of flight of the signals to each detector. Another embodiment uses an active reflective technique, where the timing is obtained through round trip transmission and reception of the signal with a known fixed delay at the vector points.

Abstract: A device for generating an acoustic stress wave in metal structures in real-time. A cylindrical housing includes a chamber, a piezostack actuator inside the chamber, and a support ring for relieving strain. The actuator has a high tensile strength block extending therefrom for contacting the surface. A pulse wave generator drives the actuator in accordance with a predetermined frequency to cause microindentation and generate an acoustic stress wave in the surface. The stress wave is transmitted to a signal transformer for producing a signal for use in systems for interpreting the signal. In a preferred embodiment, the high tensile block has a ceramic tip for engagement with the surface. The preferred piezostack actuator includes a poled element.