Abstract: Processes and devices provide parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. A device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.

Abstract: Stub shaft conveyor pulleys that may be used as a tail pulley and/or head pulley in a belt conveyor system are disclosed. The conveyor pulley includes first and second stub shaft assemblies connected to a center tube. Each stub shaft assembly includes an inner bearing and an outer bearing. In some embodiments, the outer bearing has a diameter larger than the inner bearing. Alternatively or in addition, the inner bearing may be within the center tube and the outer bearing may be exterior to the center tube.