Patents by Inventor Jeffrey Pleiss

Jeffrey Pleiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Splint-assisted enzymatic synthesis of polyribounucleotides
    Publication number: 20050130201
    Abstract: The present invention comprises methods and compositions for splint-assisted enzymatic synthesis of polyribonucleotides using an RNA polymerizing enzyme. The invention provides ligating ribonucleotides comprising ligating a donor RNA molecule to an acceptor RNA molecule in the presence of RNA ligase and a splint, wherein the donor RNA molecule is comprised of at least one nucleotide and a ligation linker moiety, the acceptor RNA molecule is comprised of at least one nucleotide and a ligation linker moiety and the splint is comprised of a polyribonucleotide. The invention also provides splints for use in splint-assisted enzymatic synthesis using an RNA polymerizing enzyme.
    Type: Application
    Filed: October 13, 2004
    Publication date: June 16, 2005
    Inventors: Michael Deras, Jeffrey Pleiss, Stephen Scaringe