Patents by Inventor Jeffrey R. Balser

Jeffrey R. Balser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isoketal scavengers and mitigation of disorders involving oxidative injury
    Patent number: 8822542
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: September 2, 2014
    Assignee: Vanderbilt University
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Venkataraman Amarnath, Prakash C. Viswanathan
  • ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY
    Publication number: 20120157501
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Application
    Filed: February 27, 2009
    Publication date: June 21, 2012
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Venkataraman Amarnath, Prakash C. Viswanathan
  • Method of preventing and/or treating oxidant injury in neurodegenerative and oxidative diseases
    Patent number: 7705054
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: April 27, 2010
    Assignee: Vanderbilt University
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Prakash C. Viswanathan, Venkataraman Amarnath
  • Human KCR1 regulation of HERG potassium channel block
    Publication number: 20030013136
    Abstract: The present invention discloses methods relating to screening methods and methods of identifying a compound that can modulate HERG potassium channel activity. The methods generally employ at least HERG and KCR1 polypeptides. The disclosed methods can be applied in the development of a candidate pharmaceutical or they can be employed to evaluate presently marketed pharmaceuticals.
    Type: Application
    Filed: October 30, 2001
    Publication date: January 16, 2003
    Inventors: Jeffrey R. Balser, Alfred L. George, Dan M. Roden