Patents by Inventor Jeffrey R. CURTIS

Jeffrey R. CURTIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers and methods for assessing myocardial infarction and serious infection risk in rheumatoid arthritis patients
    Patent number: 11946939
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: April 2, 2024
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Kerri Ford, Jeffrey R. Curtis
  • METHODS FOR CARDIOVASCULAR DISEASE IN RHEUMATOID ARTHRITIS
    Publication number: 20240077499
    Abstract: This invention includes methods for assessing and treating risk of cardiovascular disease (CVD) in a subject with an inflammatory disease, for example rheumatoid arthritis (RA). Provided are methods for assessing risk, for recommending therapy, for prognosis and monitoring, and for treatment, which are advantageously accurate for CVD in RA. The methods include measuring quantitative data for biomarkers, calculating a CVD risk score for a subject using training data, and validating the CVD risk score with a set of validation clinical data.
    Type: Application
    Filed: September 10, 2021
    Publication date: March 7, 2024
    Inventors: JEFFREY R. CURTIS, ALEXANDER GUTIN, JERRY LANCHBURY, ERIC SASSO, DARL FLAKE, ELENA HITRAYA, CHERYL CHIN
  • BIOMARKERS AND METHODS FOR ASSESSING MYOCARDIAL INFARCTION AND SERIOUS INFECTION RISK IN RHEUMATOID ARTHRITIS PATIENTS
    Publication number: 20210199671
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 1, 2021
    Applicants: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri FORD, Jeffrey R. CURTIS
  • Biomarkers and methods for assessing myocardial infarction and serious infection risk in rheumatoid arthritis patients
    Patent number: 10962552
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: March 30, 2021
    Assignees: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri Ford, Jeffrey R. Curtis
  • BIOMARKERS AND METHODS FOR ASSESSING MYOCARDIAL INFARCTION AND SERIOUS INFECTION RISK IN RHEUMATOID ARTHRITIS PATIENTS
    Publication number: 20200292559
    Abstract: Provided herein are methods for assessing risk of infection or cardiovascular disease (CVD) in a subject with an inflammatory disease, e.g., rheumatoid arthritis. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers with or without additional clinical variables to assess infection and CVD risk. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: March 10, 2020
    Publication date: September 17, 2020
    Applicants: CRESCENDO BIOSCIENCE, INC., UAB RESEARCH FOUNDATION
    Inventors: Kerri FORD, Jeffrey R. CURTIS