Abstract: An imaging guidewire that, in one embodiment, includes: (1) a hypotube forming an elongated main body having a distal end, (2) at least one multimode optical fiber integral with the hypotube and configured to carry laser light for ultrasonic excitation, (3) a single-mode optical fiber integral with the hypotube, having a reflective coating located on a distal end thereof and at the distal end of the elongated main body and configured to carry laser light for ultrasonic detection and (4) an imaging cap coupled to the elongated main body at the distal end and including a photoacoustic layer configured to receive the laser light from the at least one multimode optical fiber.

Abstract: Various devices for ablating tissue in a lateral direction and methods of operation thereof. One embodiment of such a device includes: (1) an elongated body configured to carry ablative energy from an ablative energy source associated with a proximal end to a distal end and (2) a distal tip located at the distal end, the distal tip configured to deliver the ablative energy in a direction substantially lateral to a longitudinal axis of the elongated body.