Abstract: A hydraulic system for depressurizing a work tool auxiliary circuit of a work machine. The system comprises: a power source; a reservoir of hydraulic fluid, a plurality of hydraulic lines, a pressure source, a control valve, a depressurize line connected to at least one of the plurality of hydraulic lines and the reservoir, the depressurize line includes an electromechanical valve for regulating the flow of hydraulic fluid in the depressurize line; a controller and a coupler switch comprising at least two throws and having three positions where one of the three positions actuates the electromechanical valve to depressurize the work tool auxiliary circuit. The hydraulic system can be provided as a kit to existing work machines for depressurizing the work tool hydraulic auxiliary circuit of a work machine.

Abstract: A piercing tip assembly has two piercing tips, each having two sets of piercing and shearing edges. The tip is reversible so that the tip can be detached from the shears, its orientation changed, and replaced on the shears so a fresh, sharp set of piercing and shearing edges is exposed during use. The tips are reverse by rotating each tip and replacing the tip mounted on the right side of the jaw, and switching the tip on the left side of the jaw to the right side, and the tip on the right side of the jaw to the left side. The piercing tip assembly protects a substantial portion of the upper jaw of a metal shears from wear.

Abstract: Compounds, compositions, and methods for specific inhibition of activated cdc42-associated kinase 1 (Ack1) are provided.

Abstract: Compounds, compositions, and methods for specific inhibition of activated cdc42-associated kinase 1 (Ack1) are provided.

Abstract: Compounds, compositions, and methods for specific inhibition of activated cdc42-associated kinase 1 (Ack1) are provided.

Abstract: A piercing tip assembly has two piercing tips, each having two sets of piercing and shearing edges. The tip is reversible so that the tip can be detached from the shears, its orientation changed, and replaced on the shears so a fresh, sharp set of piercing and shearing edges is exposed during use. The tips are reverse by rotating each tip and replacing the tip mounted on the right side of the jaw, and switching the tip on the left side of the jaw to the right side, and the tip on the right side of the jaw to the left side. The piercing tip assembly protects a substantial portion of the upper jaw of a metal shears from wear.

Abstract: Systems and techniques for an electronic shelf label (ESL) comprising two displays disposed on opposing sides of the ESL are described. The dual sided ESL of the present invention allows a retailer to display price, merchandising and operational information to consumers and store employees from multiple viewing angles utilizing a single ESL. In one aspect, the ESL is mounted perpendicular to a shelf rail, allowing visibility to both sides. This perpendicular mounting technique requires less linear space along the shelf rail, allowing product density to be increased for small products. In another aspect, the ESL is mounted on a free standing housing, allowing the ESL to be placed on various displays throughout the retail establishment. The ESL in accordance with the present invention may display the same information on both sides of the ESL. In another aspect, the ESL may display different information on each side of the ESL.