Patents by Inventor Jeffrey Rohde

Jeffrey Rohde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 7351828
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: April 1, 2008
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME
    Publication number: 20070179186
    Abstract: The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme, The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 10, 2007
    Publication date: August 2, 2007
    Inventors: Jeffrey Rohde, Qi Shuai, James Link, Jyoti Patel, Jurgen Dinges, Bryan Sorensen, Hong Yong, Vince Yeh, Ravi Kurukulasuriya
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
    Publication number: 20060281773
    Abstract: The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: January 5, 2006
    Publication date: December 14, 2006
    Inventors: Jyoti Patel, Qi Shuai, James Link, Jeffrey Rohde, Jurgen Dinges, Bryan Sorensen, Martin Winn, Hong Yong, Vince Yeh
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
    Publication number: 20060149070
    Abstract: The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: January 5, 2006
    Publication date: July 6, 2006
    Inventors: Jeffrey Rohde, Qi Shuai, James Link, Jyoti Patel, Jurgen Dinges, Bryan Sorensen, Hong Yong, Vince Yeh, Ravi Kurukulasuriya
  • Metabolic stabilization of substituted adamantane
    Publication number: 20060148871
    Abstract: The present invention is directed to the method of increasing the metabolic stability of adamantane containing compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 (11-beta-HSD-1) enzyme. The stability is achieved by substitutions of the adamantane ring.
    Type: Application
    Filed: January 5, 2006
    Publication date: July 6, 2006
    Inventors: Jeffrey Rohde, Liping Pan, Marina Pliushchev, James Link
  • Benzimidazoles that are useful in treating male sexual dysfunction
    Patent number: 7022728
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: April 4, 2006
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
    Publication number: 20050277647
    Abstract: The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 29, 2005
    Publication date: December 15, 2005
    Inventors: James Link, Yixian Chen, Hwan-Soo Jae, Jyoti Patel, Marina Pliushchev, Jeffrey Rohde, Qi Shuai, Bryan Sorensen, Martin Winn, Dariusz Wodka, Hong Yong
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their therapeutic application
    Publication number: 20050261302
    Abstract: The present invention relates to the use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment or prophylactically treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 28, 2005
    Publication date: November 24, 2005
    Inventors: Ethan Hoff, James Link, Marina Pliushchev, Jeffrey Rohde, Martin Winn
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their therapeutic application
    Publication number: 20050245532
    Abstract: The present invention relates to the use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment or prophylactically treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 29, 2004
    Publication date: November 3, 2005
    Inventors: Ethan Hoff, James Link, Marina Pliushchev, Jeffrey Rohde, Martin Winn
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenaseType 1 enzyme and their therapeutic application
    Publication number: 20050245533
    Abstract: The present invention relates to the use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment or prophylactically treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions mediated by excessive glucocorticoid action.
    Type: Application
    Filed: October 14, 2004
    Publication date: November 3, 2005
    Inventors: Ethan Hoff, James Link, Marina Pliushchev, Jeffrey Rohde, Martin Winn
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
    Publication number: 20050245534
    Abstract: The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: October 14, 2004
    Publication date: November 3, 2005
    Inventors: James Link, Marina Pliushchev, Jeffrey Rohde, Dariusz Wodka, Jyoti Patel, Qi Shuai
  • Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
    Publication number: 20050245745
    Abstract: The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
    Type: Application
    Filed: April 29, 2004
    Publication date: November 3, 2005
    Inventors: James Link, Marina Pliushchev, Jeffrey Rohde, Dariusz Wodka
  • Benzimidazoles that are useful in treating sexual dysfunction
    Patent number: 6960589
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein L is C1-4 alkyl; RA, RB, RC, RD, and RE, are as described in the specification; Z is selected from the group consisting of N, C and CH; and A is aryl and heteroaryl as described in the specification.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: November 1, 2005
    Assignee: Abbott Laboratories
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde, Kenneth M. Engstrom
  • Benzimidazoles that are useful in treating sexual dysfunction
    Publication number: 20040110766
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: October 31, 2003
    Publication date: June 10, 2004
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Indazole derivatives that are activators of soluble guanylate cyclase
    Publication number: 20040048866
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: February 26, 2003
    Publication date: March 11, 2004
    Inventors: Teodozyj Kolasa, Jorge D. Brioni, Vijaya Gracias, Masaki Nakane, Meena V. Patel, Jeffrey Rohde
  • Benzimidazoles that are useful in treating sexual dysfunction
    Publication number: 20030162790
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: September 6, 2002
    Publication date: August 28, 2003
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde, Kenneth M. Engstrom
  • 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use
    Publication number: 20030073850
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: February 17, 2000
    Publication date: April 17, 2003
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll, Xenia Searle, Fan Yang
  • Imidazoles and related compounds as &agr;1A agonists
    Patent number: 6503935
    Abstract: Compounds having formula I: are useful in treating diseases prevented by or ameliorated with &agr;1A agonists. Also disclosed are &agr;1A agonist compositions and a method of activating &agr;1 adrenoceptors in a mammal.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: January 7, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Jr., Mark W. Holladay, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll
  • Benzimidazoles that are useful in treating sexual dysfunction
    Publication number: 20020169167
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: March 8, 2002
    Publication date: November 14, 2002
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde
  • Benzimidazoles that are useful in treating sexual dysfunction
    Publication number: 20020169166
    Abstract: The present invention relates to the use of compounds of formula (I) 1
    Type: Application
    Filed: December 14, 2001
    Publication date: November 14, 2002
    Inventors: Marlon D. Cowart, Pramila A. Bhatia, Jerome F. Daanen, Andrew O. Stewart, Meena V. Patel, Teodozyj Kolasa, Jorge D. Brioni, Jeffrey Rohde