Patents by Inventor Jeffrey Romine

Jeffrey Romine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cycloalkyl heterocycles for treating hepatitis C virus
    Patent number: 7112601
    Abstract: Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: September 26, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Peter W. Glunz, Brent D. Douty, Scott W. Martin, Jeffrey Romine
  • Inhibitors of HCV replication
    Publication number: 20050119318
    Abstract: Compounds having the structure of formula (I) are disclosed. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular the function of the HCV NS5B protein.
    Type: Application
    Filed: October 27, 2004
    Publication date: June 2, 2005
    Inventors: Thomas Hudyma, Xiaofan Zheng, Jeffrey Romine
  • Iminothiazolidinones as inhibitors of HCV replication
    Publication number: 20050096364
    Abstract: Compounds having the structure of formula I are described wherein R, R?, R1, R2, and R3 are as defined in the specification. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular the function of the HCV NS5A protein.
    Type: Application
    Filed: August 8, 2003
    Publication date: May 5, 2005
    Inventors: Jeffrey Romine, Scott Martin, Lawrence Snyder, Michael Serrano-Wu, Milind Deshpande, Darren Whitehouse, Julie Lemm, Donald O'Boyle, Min Gao, Richard Colonno
  • Cycloalkyl heterocycles for treating Hepatitis C virus
    Publication number: 20050075376
    Abstract: Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C. Compositions and methods of using these compounds are also disclosed.
    Type: Application
    Filed: August 19, 2004
    Publication date: April 7, 2005
    Inventors: Peter Glunz, Brent Douty, Scott Martin, Jeffrey Romine
  • Combination pharmaceutical agents as inhibitors of HCV replication
    Publication number: 20050069522
    Abstract: Disclosed are combination pharmaceutical agents for the treatment of an HCV infection comprising a compound effective to inhibit the function of the HCV NS5A protein and another compound having anti-HCV activity. Compounds which can inhibit the function of the NS5A protein having the structure of formula I are described wherein R, R?, R1, R2, and R3 are as defined in the specification. The other compounds having anti-HCV activity are effective to inhibit the function of a target selected from the group consisting of HCV metalloprotease, HCV serine protease, HCV polymerase, HCV helicase, HCV NS4B protein, HCV entry, HCV assembly, HCV egress, HCV NS5A protein, IMPDH and a nucleoside analog for the treatment of an HCV infection.
    Type: Application
    Filed: August 8, 2003
    Publication date: March 31, 2005
    Inventors: Richard Colonno, Julie Lemm, Donald O'Boyle, Min Gao, Jeffrey Romine, Scott Martin, Lawrence Snyder, Michael Serrano-Wu, Milind Deshpande, Darren Whitehouse