Patents by Inventor Jeffrey Ross

Jeffrey Ross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of Resected Liver Serum for Whole Liver-Engineering
    Publication number: 20250025602
    Abstract: The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained following a partial hepatectomy, to increase the engraftment, proliferation and/or functionality of cells on a biocompatible scaffold.
    Type: Application
    Filed: July 29, 2024
    Publication date: January 23, 2025
    Inventors: Jeffrey ROSS, Anne YOUNG, Allie HAARSTAD, Scott NYBERG
  • Use of resected liver serum for whole liver-engineering
    Patent number: 12076461
    Abstract: The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained following a partial hepatectomy, to increase the engraftment, proliferation and/or functionality of cells on a biocompatible scaffold.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: September 3, 2024
    Assignees: Miromatrix Medical Inc., Mayo Foundation for Medical Education & Research, Mayo Medical Ventures
    Inventors: Jeffrey Ross, Anne Young, Allie Haarstad, Scott Nyberg
  • CD274 MUTATIONS FOR CANCER TREATMENT
    Publication number: 20240263240
    Abstract: Provided herein are methods related to detecting CD274 gene mutations, as well as methods of treatment, uses, and kits related thereto. Detection of CD274 gene mutations can be used to identify individuals that may or may not benefit from an anti-cancer therapy.
    Type: Application
    Filed: May 13, 2022
    Publication date: August 8, 2024
    Applicant: Foundation Medicine, Inc.
    Inventors: Richard Sheng Poe HUANG, Brennan DECKER, Jeffrey ROSS
  • BIOMARKERS FOR CANCER TREATMENT
    Publication number: 20240110230
    Abstract: The present disclosure provides biomarkers associated with cancers, such as urothelial bladder cancer, non-small cell lung cancer, and renal cell carcinoma, as well as methods, kits and reagents for detecting such biomarkers. The disclosure also provides methods for evaluating, identifying, assessing, and/or treating an individual having a cancer, such as a urothelial bladder cancer, non-small cell lung cancer, and renal cell carcinoma.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 4, 2024
    Applicant: Foundation Medicine, Inc.
    Inventor: Jeffrey ROSS
  • USE OF PERFUSION DECELLULARIZED LIVER FOR ISLET CELL RECELLULARIZATION
    Publication number: 20230293770
    Abstract: The invention provides a method to prepare a graft comprising a recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof, and a method of using the recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof.
    Type: Application
    Filed: August 17, 2022
    Publication date: September 21, 2023
    Inventor: Jeffrey Ross
  • Methods of Decellularization and Recellularization of Organs and Portions of Organs
    Publication number: 20230015009
    Abstract: Disclosed herein are compositions and methods to decellularize an isolated organ or portion thereof. Also disclosed herein are compositions and methods for treatment of disease utilizing a decellularized or recellularized organ. Also disclosed herein are methods of improving decellularization and/or recellularization of an isolated organ or portion thereof.
    Type: Application
    Filed: December 4, 2019
    Publication date: January 19, 2023
    Inventors: Jeffrey ROSS, Aron STUMBRAS, Brett ANDERSON, Aleks KATANE, Emily BECK, Joseph UZARSKI
  • Use of Resected Liver Serum for Whole Liver-Engineering
    Publication number: 20220323645
    Abstract: The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained following a partial hepatectomy, to increase the engraftment, proliferation and/or functionality of cells on a biocompatible scaffold.
    Type: Application
    Filed: February 7, 2022
    Publication date: October 13, 2022
    Inventors: Jeffrey ROSS, Anne YOUNG, Allie HAARSTAD, Scott NYBERG
  • Use of perfusion decellularized liver for islet cell recellularization
    Patent number: 11452797
    Abstract: The invention provides a method to prepare a graft comprising a recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof, and a method of using the recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: September 27, 2022
    Assignee: Miromatrix Medical Inc.
    Inventor: Jeffrey Ross
  • SEALING OF DECELLULARIZED AND RECELLULARIZED ENGINEERED ORGAN GRAFTS
    Publication number: 20220280695
    Abstract: The disclosure provides for methods of sealing of decellularized and recellularized engineered organ grafts, thereby providing a reinforced (fortified) decellularized and recellularized engineered organ graft.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 8, 2022
    Inventors: Aleksandr Katane, Jeffrey Ross, Dominique Davidow, Shawn Riesgraf
  • Improved Decellularization of Isolated Organs
    Publication number: 20220152276
    Abstract: Disclosed herein are compositions and methods to decellularize an isolated organ or portion thereof. Also disclosed herein are compositions and methods for treatment of disease utilizing a decellularized or recellularized organ. Also disclosed herein are methods of improving decellularization and/or recellularization of an isolated organ or portion thereof.
    Type: Application
    Filed: March 20, 2020
    Publication date: May 19, 2022
    Inventors: Anne YOUNG, Aleksandr KATANE, Ben STEINER, Brian PERRAULT, Dominique Seetapun DAVIDOW, Jeffrey ROSS
  • METHOD OF DEHYDRATION OF EXTRACELLULAR MATRIX AND PARTICLES FORMED THEREFROM
    Publication number: 20220088269
    Abstract: A method of extracellular matrix (ECM) particle formation, and compositions produced by the method, are provided.
    Type: Application
    Filed: January 7, 2020
    Publication date: March 24, 2022
    Inventors: Ben Steiner, Dominique Davidow, Aleksandr Katane, Jeffrey Ross
  • Use of resected liver serum for whole liver-engineering
    Patent number: 11278643
    Abstract: The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained following a partial hepatectomy, to increase the engraftment, proliferation and/or functionality of cells on a biocompatible scaffold.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: March 22, 2022
    Assignees: Mayo Foundation for Medical Education and Research, Miromatrix Medical Inc.
    Inventors: Jeffrey Ross, Anne Young, Allie Haarstad, Scott Nyberg
  • METHODS OF LIVER RECELLULARIZATION
    Publication number: 20210322642
    Abstract: Disclosed herein are recellularized livers prepared from decellularized liver extracellular matrices. Also disclosed herein are kits and systems comprising a recellularized liver as described herein. Also disclosed herein are methods of recellularizing livers from decellularized liver extracellular matrices.
    Type: Application
    Filed: December 4, 2020
    Publication date: October 21, 2021
    Inventors: Jeffrey ROSS, Dominique Seetapun DAVIDOW, Ben STEINER
  • USE OF PERFUSION DECELLULARIZED LIVER FOR ISLET CELL RECELLULARIZATION
    Publication number: 20190381212
    Abstract: The invention provides a method to prepare a graft comprising a recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof, and a method of using the recellularized extracellular matrix of a mammalian liver, liver lobe or portion thereof.
    Type: Application
    Filed: January 9, 2019
    Publication date: December 19, 2019
    Inventor: Jeffrey ROSS
  • Use of perfusion decellularized liver for islet cell recellularization
    Patent number: 10213525
    Abstract: The invention provides a method for preparing a perfusion based islet cell containing extracellular matrix of liver, an islet cell recellularized extracellular matrix, and methods of using the recellularized matrix.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: February 26, 2019
    Assignee: Micromatrix Medical, Inc.
    Inventor: Jeffrey Ross
  • Gas filled decellularized matrix
    Patent number: 9974814
    Abstract: A method to provide an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, and uses thereof, are provided.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: May 22, 2018
    Assignee: Miromatrix Medical Inc.
    Inventors: Aleksandr Katane, Dominique Seetapun, Jeffrey Ross
  • USE OF RESECTED LIVER SERUM FOR WHOLE LIVER-ENGINEERING
    Publication number: 20180064848
    Abstract: The disclosure provides a method of using blood or fractions thereof, e.g., serum, obtained from a mammal subjected to liver surgery, for example, obtained following a partial hepatectomy, to increase the engraftment, proliferation and/or functionality of cells on a biocompatible scaffold.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 8, 2018
    Inventors: Jeffrey Ross, Anne Young, Allie Haarstad, Scott Nyberg
  • GAS FILLED DECELLULARIZED MATRIX
    Publication number: 20160279170
    Abstract: A method to provide an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, an inflated decellularized extracellular matrix of a mammalian organ or a vascularized portion thereof, or a mammalian vascularized tissue or a vascularized portion thereof, and uses thereof, are provided.
    Type: Application
    Filed: March 24, 2016
    Publication date: September 29, 2016
    Inventors: Aleksandr Katane, Dominique Seetapun, Jeffrey Ross
  • Methods of decellularizing bone
    Patent number: 9290738
    Abstract: The invention provides methods for decellularizing bone, e.g., human bone.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: March 22, 2016
    Assignee: Miromatrix Medical Inc.
    Inventors: Jeffrey Ross, Blaise Porter
  • USE OF MICROPARTICLES AND ENDOTHELIAL CELLS WITH DECELLULARIZED ORGANS AND TISSUES
    Publication number: 20160030637
    Abstract: The invention provides a method for maintaining capillary lumen diameter, reducing a decrease in capillary vessel lumen diameter or expanding capillary vessel lumen diameter in a re-endothelialized decellularized organ or tissue graft with an intact extracellular matrix vascular network. The method is based on administration of endothelial cells and microparticles to the decellularized ECM.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Inventors: Jeffrey Ross, Dominique Seetapun