Abstract: Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for the treatment of hypertension.

Abstract: Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for the treatment of hypertension.

Abstract: The present invention is directed to a pigment dispersant composition for use with inorganic pigments in coating compositions. The dispersant composition includes a vinyl or acrylic copolymer and a transition metal or rare earth metal salt. The metal salt in combination with the copolymer is useful with inorganic pigment as it lowers the viscosity of the pigment dispersions, thus allowing a higher concentration of pigment in the dispersion and consequently providing dispersions with higher non-volatile content and higher pigment to binder ratios. The presence of the metal salts in the dispersant composition when used with surface coated metal flake pigment provides excellent corrosion reduction of the metal pigment, indicated by the reduction or elimination of hydrogen gassing by the pigment in a coating composition.

Abstract: The present invention relates to ionic and nonionic polyamide modified polyurethane polymers for use in coating compositions, a method for forming the polymer and coating compositions containing these polymers. The polyamide modified polyurethane polymers of the present invention include polyamide formed from aromatic, aliphatic, or cycloaliphatic anhydrides or diacid halides and an amine containing compound such as amino alcohol, amino thiol, diamine or mixtures thereof, wherein the reactive terminii of the polyamide ere substituted by hydroxyl or thiol functional groups, together with a chain extending alcohol and diisocyanate functional monomer.

Abstract: The present invention is directed to a pigment dispersant composition for use with inorganic pigments in coating compositions. The dispersant composition includes a vinyl or acrylic copolymer and a transition metal or rare earth metal salt. The metal salt in combination with the copolymer is useful with inorganic pigment as it lowers the viscosity of the pigment dispersions, thus allowing a higher concentration of pigment in the dispersion and consequently providing dispersions with higher non-volatile content and higher pigment to binder ratios. The presence of the metal salts in the dispersant composition when used with surface coated metal flake pigment provides excellent corrosion reduction of the metal pigment, indicated by the reduction or elimination of hydrogen gassing by the pigment in a coating composition.

Abstract: The invention is an aluminum flake pigment particle, surface treated transition metal or rare earth metal salt. The treated pigment particle has been found to be highly useful in water-borne coating compositions having a basic pH. The treated pigment particles experience significantly less hydrogen gassing in a high pH environment, and in water-borne coating compositions than untreated aluminum flake pigment particles. The treated pigment particles are also useful when combined with a pigment dispersant composition to further inhibit corrosion and gassing when the pigments are used in a coating composition.

Abstract: The invention is a slightly water-soluble, time release corrosion inhibitor compound for treating aluminum flake pigment. The corrosion inhibitor is the reaction product of a water-soluble metal salt including metals selected from the group consisting of yttrium and rare earth metals and an anionic metal salt including transition metal oxo-complexes and soluble salts of silicon and mixtures thereof. The corrosion inhibitor is useful for preventing hydrogen gassing of aluminum pigment particles. The compound is particularly useful for preventing gassing of bare and chromated aluminum pigment particles in aqueous compositions and in water-borne coating compositions having a basic pH. The pigment particles used in combination with the corrosion inhibitors of the present invention experience significantly less hydrogen gassing in a high pH aqueous environment and in water-borne coating compositions having high pH, than aluminum flake pigment particles and coatings without the corrosion inhibitor.