Abstract: A method of spontaneously patterning a polymer during frontal polymerization includes activating an initiation region of a monomer solution to reaction to initiate a polymerization reaction. A polymerization front is generated and propagates through the monomer solution in a radial or longitudinal direction away from the initiation region. The monomer solution is spontaneously heated downstream of the polymerization front by thermal transport away from the polymerization reaction. Once a localized region of the monomer solution reaches a temperature sufficient for spontaneous initiation of another polymerization reaction, a new polymerization front is generated and propagates through the monomer solution in a circumferential or transverse direction.

Abstract: An energetic composition and a method of unzipping polymer binders are disclosed, which includes localizing a heat feedback just near the reaction front by unzipping polymer binders employed to a nanothermite. The energetic composition includes an unzipping polymer binder employed to high load fuel and oxidizer particles.

Abstract: Thermoset resin compositions including a compound of formula (I) having a working life and/or a pot life of at least 1 hour are provided. Copolymers prepared from the thermoset resin compositions are further provided. Methods of preparing and polymerizing the thermoset resin compositions are further provided. Delivery devices for preparing thermoset resin compositions are further provided.

Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

Abstract: Methods of preparing oligomers including heating a mixture of an amount of a functionalized cycloalkene, an amount of a chain transfer agent, a phosphite ester, and a catalyst, a degree of polymerization of the oligomers controllable by a molar ratio of the amount of the functionalized cycloalkene to the amount of the chain transfer agent, are provided herein. Methods of preparing polymers including heating the oligomers and a second amount of the functionalized cycloalkene, a phosphite ester, and a catalyst are further provided. Compositions of oligomers and functionalized cycloalkenes are further provided.

Abstract: Compounds of formula (I) are provided. Polymers including monomers of formula (II) are further provided. Methods of releasing controlled amounts of a small molecule from the polymers are further provided. Devices for releasing controlled amounts of a small molecule are further provided.

Abstract: Methods for recycling oligomeric units derived from a first polymer into a second polymer are provided herein. Methods of preparing oligomeric macromonomers from oligomeric units are further provided. Methods of polymerizing oligomeric macromonomers are further provided.

Abstract: Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

Abstract: A frontally polymerized polymeric body includes, according to a first embodiment, a deformable polymer comprising polydicyclopentadiene (pDCPD) and/or poly(5-ethylidene-2-norbornene) (pENB), where the deformable polymer has a fracture strain of at least about 0.5 mm mm?1. According to a second embodiment, the frontally polymerized polymeric body includes a first polymer comprising pDCPD and/or pENB, and a second polymer adjacent to the first polymer also comprising the pDCPD and/or the pENB. The second polymer is more or less deformable than the first polymer. Thus, the frontally polymerized polymeric body exhibits spatially varying mechanical and/or other properties.

Abstract: A method of light-promoted frontal ring-opening metathesis polymerization includes providing a monomer solution including dicyclopentadiene, a ruthenium-based catalyst and a phosphite inhibitor, and exposing the monomer solution to ultraviolet light having a wavelength in a range from 315 nm to 400 nm, thereby initiating an exothermic polymerization reaction and generating a self-propagating polymerization front. The polymerization front moves through the monomer solution and polymerizes the dicyclopentadiene.

Abstract: Provided herein are compositions and methods for mechanochemical dynamic therapy.

Abstract: A method of rapidly forming an elastomer with tunable properties is described herein. The method includes preparing a monomer solution comprising a catalyst and one or more monomers including 1,5-cyclooctadiene (COD). The one or more monomers may further include dicyclopentadiene (DCPD), and each of the COD and the DCPD may be present in the monomer solution at a predetermined volume percentage. A region of the monomer solution is activated to initiate an exothermic polymerization reaction and generate a self-propagating polymerization front, which moves through the monomer solution and polymerizes the one or more monomers. Thus, an elastomer having predetermined properties is rapidly formed.

Abstract: A frontally polymerized polymeric body includes, according to a first embodiment, a deformable polymer comprising polydicyclopentadiene (pDCPD) and/or poly(5-ethylidene-2-norbornene) (pENB), where the deformable polymer has a fracture strain of at least about 0.5 mm mm?1. According to a second embodiment, the frontally polymerized polymeric body includes a first polymer comprising pDCPD and/or pENB, and a second polymer adjacent to the first polymer also comprising the pDCPD and/or the pENB. The second polymer is more or less deformable than the first polymer. Thus, the frontally polymerized polymeric body exhibits spatially varying mechanical and/or other properties.

Abstract: A method of forming a void, channel and/or vascular network in a polymeric matrix comprises providing a pre-vascularized structure that includes a matrix material and a sacrificial material embedded in the matrix material in a predetermined pattern, where the matrix material comprises a monomer and the sacrificial material comprises a polymer. A region of the matrix material is activated to initiate an exothermic polymerization reaction and generate a self-propagating polymerization front. As the polymerization front propagates through the matrix material and polymerizes the monomer, heat from the exothermic reaction simultaneously degrades the sacrificial material into a gas-phase and/or liquid-phase byproduct. Thus, one or more voids or channels having the predetermined pattern are rapidly formed in the matrix material.

Abstract: Intermittent energy sources, including solar and wind, require scalable, low-cost, multi-hour energy storage solutions to be effectively incorporated into the grid. Redox-flow batteries offer a solution, but suffer from rapid capacity fade and low Coulombic efficiency due to the high permeability of redox-active species across the battery's membrane. Here we show that active-species crossover can be arrested by scaling the membrane's pore size to molecular dimensions and in turn increasing the size of the active material to be above the membrane's pore-size exclusion limit. When oligomeric redox-active organic molecules were paired with microporous polymer membranes, the rate of active-material crossover was either completely blocked or slowed more than 9,000-fold compared to traditional separators at minimal cost to ionic conductivity. In the case of the latter, this corresponds to an absolute rate of ROM crossover of less than 3 ?mol cm?2 day?1 (for a 1.

Abstract: The present disclosure provides multivalent polymer-peptide conjugate compositions capable of breaking already formed amyloid fibrils. Also provided are methods of treating a subject having or suspected of having Alzheimer's disease by administering a therapeutically effective amount of these multivalent polymer-peptide conjugate compositions.

Abstract: A method of light-promoted frontal ring-opening metathesis polymerization includes providing a monomer solution including dicyclopentadiene, a ruthenium-based catalyst and a phosphite inhibitor, and exposing the monomer solution to ultraviolet light having a wavelength in a range from 315 nm to 400 nm, thereby initiating an exothermic polymerization reaction and generating a self-propagating polymerization front. The polymerization front moves through the monomer solution and polymerizes the dicyclopentadiene.

Abstract: A partially degradable polymeric fiber includes a thermally degradable polymeric core and a coating surrounding at least a portion of the core. The thermally degradable polymeric core includes a polymeric matrix including a poly(hydroxy-alkanoate), and a metal selected from the group consisting of an alkali earth metal and a transition metal, in the core polymeric matrix. The concentration of the metal in the polymeric matrix is at least 0.1 wt %. The partially degradable polymeric fiber may be used to form a microvascular system containing one or more microfluidic channels.

Abstract: The present disclosure provides a composition of matter comprising purified cyclic poly(phthalaldehyde) (cPPA) and a plasticizer. The composition enables thermal processing and molding in bulk quantities, and is designed to degrade when contacted by an acid or exposed to a high enough temperature. Photodegradable cPPA containing a photooxidant is disclosed. Methods of making and recycling the composition of matter are also provided.

Abstract: The present disclosure provides a novel method of 3D printing using frontal polymerization chemistry. This method enables the printing of tough, high quality thermosets in a short time with the option of adding fiber reinforcement. As such, it facilitates fabrication of mechanically robust 3D-printed devices and structures.