Patents by Inventor Jeffrey S. Sakamoto
Jeffrey S. Sakamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230323050Abstract: Provided herein is technology relating to materials having microscale and/or nanoscale features and particularly, but not exclusively, to porous materials comprising microscale features, methods for producing porous materials comprising microscale features, drug delivery vehicles, and related kits, systems, and uses.Type: ApplicationFiled: March 24, 2023Publication date: October 12, 2023Inventors: Mark H. Tuszynski, Jeffrey S. Sakamoto, Kendell M. Pawelec, Yacov Koffler, Michael Sailor, Jonathan Zuidema
-
Patent number: 11680143Abstract: Provided herein is technology relating to materials having microscale and/or nanoscale features and particularly, but not exclusively, to porous materials comprising microscale features, methods for producing porous materials comprising microscale features, drug delivery vehicles, and related kits, systems, and uses.Type: GrantFiled: January 9, 2020Date of Patent: June 20, 2023Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Mark H. Tuszynski, Jeffrey S. Sakamoto, Kendell M. Pawelec, Yacov M. Koffler, Michael Sailor, Jonathan Zuidema
-
Publication number: 20210353833Abstract: Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ?about 100 ?m that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.Type: ApplicationFiled: July 22, 2021Publication date: November 18, 2021Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRSInventors: Jeffrey S. SAKAMOTO, Dena SHAHRIARI, Mark H. TUSZYNSKI, Wendy CAMPANA, Yacov KOFFLER
-
Patent number: 11110207Abstract: Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ?about 100 ?m that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.Type: GrantFiled: August 20, 2019Date of Patent: September 7, 2021Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, The United States Government as represented by the Department of Veterans AffairsInventors: Jeffrey S. Sakamoto, Dena Shahriari, Mark H. Tuszynski, Wendy Campana, Yacov Koffler
-
Publication number: 20200388854Abstract: The present disclosure relates to electrochemical devices, such as lithium battery electrodes, and solid-state lithium ion and lithium metal batteries including these electrodes. This invention also relates to methods for making such electrochemical devices. The present disclosure provides a porous ceramic-metal (cermet) cathode for supporting the solid electrolyte in a battery whereby the conductive additive adheres cathode particles and is the conductive diluent. The cermet cathode is processed to not only achieve adequate mechanical integrity to support thin solid-electrolyte layers but also to include interconnected porosity to allow permeating of a liquid, gel, or polymer electrolyte.Type: ApplicationFiled: May 26, 2020Publication date: December 10, 2020Inventors: JEFFREY S. SAKAMOTO, NATHAN JOHN TAYLOR
-
Publication number: 20200354533Abstract: Provided herein is technology relating to materials having microscale and/or nanoscale features and particularly, but not exclusively, to porous materials comprising microscale features, methods for producing porous materials comprising microscale features, drug delivery vehicles, and related kits, systems, and uses.Type: ApplicationFiled: January 9, 2020Publication date: November 12, 2020Inventors: Mark H. Tuszynski, Jeffrey S. Sakamoto, Kendell M. Pawelec, Yacov M. Koffler, Michael Sailor, Jonathan Zuidema
-
Publication number: 20200000971Abstract: Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ?about 100 ?m that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.Type: ApplicationFiled: August 20, 2019Publication date: January 2, 2020Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRSInventors: Jeffrey S. SAKAMOTO, Dena SHAHRIARI, Mark H. TUSZYNSKI, Wendy CAMPANA, Yacov KOFFLER
-
Patent number: 10426872Abstract: Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ?about 100 ?m that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.Type: GrantFiled: October 7, 2016Date of Patent: October 1, 2019Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, The United States Of America As Represented By The Department Of Veterans AffairsInventors: Jeffrey S. Sakamoto, Dena Shahriari, Mark H. Tuszynski, Wendy Campana, Yacov Koffler
-
Publication number: 20180280580Abstract: Tissue scaffolds for neural tissue growth have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall having a thickness of ?about 100 ?m that is formed from a biocompatible and biodegradable material comprising a polyester polymer. The polyester polymer may be polycaprolactone, poly(lactic-co-glycolic acid) polymer, and combinations thereof. The tissue scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. In other aspects, methods of making such tissue scaffolds are provided. Such a method may include mixing a reduced particle size porogen with a polymeric precursor solution. The material is cast onto a template and then can be processed, including assembly in a sheath and removal of the porogen, to form a tissue scaffold having a plurality of porous microchannels.Type: ApplicationFiled: October 7, 2016Publication date: October 4, 2018Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRSInventors: Jeffrey S. SAKAMOTO, Dena SHAHRIARI, Mark H. TUSZYNSKI, Wendy CAMPANA, Yacov KOFFLER
-
Patent number: 7480984Abstract: A method of applying a physical barrier to suppress thermal decomposition near a surface of a thermoelectric material including applying a continuous metal foil to a predetermined portion of the surface of the thermoelectric material, physically binding the continuous metal foil to the surface of the thermoelectric material using a binding member, and heating in a predetermined atmosphere the applied and physically bound continuous metal foil and the thermoelectric material to a sufficient temperature in order to promote bonding between the continuous metal foil and the surface of the thermoelectric material. The continuous metal foil forms a physical barrier to enclose a predetermined portion of the surface. Thermal decomposition is suppressed at the surface of the thermoelectric material enclosed by the physical barrier when the thermoelectric element is in operation.Type: GrantFiled: June 7, 2004Date of Patent: January 27, 2009Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Jeffrey S. Sakamoto, Thierry Caillat, Jean-Pierre Fleurial, G. Jeffrey Snyder