Abstract: Compounds that inhibit p38? MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

Abstract: The present invention is directed toward a new and improved compactor or packer. The compactor, which may be used to compact refuse, includes a container, a track disposed within the container, and a ball screw rotatably disposed within the track. The compactor further includes a ball nut operatively coupled around the ball screw, where rotation of the ball screw causes the ball nut to move along or traverse the ball screw. A packer blade is coupled to the ball nut via a floating interface. Movement of the ball nut long the ball screw due to rotation of the ball screw forces the packer blade to move within the container. The floating interface allows the packer blade to float within the container with respect to the ball nut to reduce the likelihood of binding of the ball nut on the ball screw as the packer blade traverses within the container.

Abstract: A variable booster device of a pneumatic regenerative system of a motorized vehicle is in fluid communication with a pneumatic device of the system. The variable booster device includes a main body and a plate slidingly coupled to the main body. The main body includes an inlet, an outlet, and an interior cavity. The plate is reconfigurable between a first configuration, where the outlet is a first size, and a second configuration, where the outlet is a second size. The variable booster device pressurizes the air a first amount when the plate is in the first configuration and pressurizes the air a second amount when the plate is in the second configuration, where the second amount is greater than the first amount. Disposed within the interior cavity is a first helical screw rotor and a second helical screw rotor. The two helical screw rotors are intermeshed with one another.

Abstract: The present invention is directed toward a new and improved compactor or packer. The compactor, which may be used to compact refuse, includes a container, a track disposed within the container, and a ball screw rotatably disposed within the track. The compactor further includes a ball nut operatively coupled around the ball screw, where rotation of the ball screw causes the ball nut to move along or traverse the ball screw. A packer blade is coupled to the ball nut via a floating interface. Movement of the ball nut long the ball screw due to rotation of the ball screw forces the packer blade to move within the container. The floating interface allows the packer blade to float within the container with respect to the ball nut to reduce the likelihood of binding of the ball nut on the ball screw as the packer blade traverses within the container.

Abstract: A two-way flow rotary valve for a reversible compressor is disclosed. The two-way flow rotary valve comprises a tubular member with a first end and a second end. Two or more low friction face seals are disposed around the tubular member between the first end and the second end and a central section is disposed between the two or more low friction face seals. The two or more low friction face seals allow the central section to rotate within a substantially cylindrical receiver of a cylinder head. A gas port extends through the tubular member and is configured to allow the rotary valve to selectively exchange gas with a cylinder (when used as a compressor and when used as an air motor).

Abstract: A variable booster device of a pneumatic regenerative system of a motorized vehicle is in fluid communication with a pneumatic device of the system. The variable booster device includes a main body and a plate slidingly coupled to the main body. The main body includes an inlet, an outlet, and an interior cavity. The plate is reconfigurable between a first configuration, where the outlet is a first size, and a second configuration, where the outlet is a second size. The variable booster device pressurizes the air a first amount when the plate is in the first configuration and pressurizes the air a second amount when the plate is in the second configuration, where the second amount is greater than the first amount. Disposed within the interior cavity is a first helical screw rotor and a second helical screw rotor. The two helical screw rotors are intermeshed with one another.