Patents by Inventor Jeffrey Spalazzi

Jeffrey Spalazzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomimmetic nanofiber scaffold for soft tissue and soft tissue-to-bone repair, augmentation and replacement
    Patent number: 10265155
    Abstract: An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: April 23, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kristen L. Moffat, William N. Levine
  • Non-invasive suture anchor and method
    Patent number: 9848867
    Abstract: A non-invasive device for anchoring a suture includes a sheet to which a suture can be attached and an adhesive that can affix the sheet to bone. The method provides placing effective amount of an adhesive on a bone and attaching the suture to the adhesive and allowing the adhesive to set.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: December 26, 2017
    Assignee: HOWMEDICA OSTEONICS CORP.
    Inventors: Renwen Zhang, Twana Davisson, Jeffrey Spalazzi, Venkat R. Garigapati, Matthew E. Murphy, Anthony P. Napolitano
  • Multi-phased, biodegradable and oesteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
    Patent number: 9427495
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: August 30, 2016
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kathie Kionisio
  • BIOMIMMETIC NANOFIBER SCAFFOLD FOR SOFT TISSUE AND SOFT TISSUE-TO-BONE REPAIR, AUGMENTATION AND REPLACEMENT
    Publication number: 20150100121
    Abstract: An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering.
    Type: Application
    Filed: September 30, 2014
    Publication date: April 9, 2015
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kristen L. Moffat, William N. Levine
  • MULTI-PHASED, BIODEGRADABLE AND OESTEOINTEGRATIVE COMPOSITE SCAFFOLD FOR BIOLOGICAL FIXATION OF MUSCULOSKELETAL SOFT TISSUE TO BONE
    Publication number: 20150024063
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Application
    Filed: August 4, 2014
    Publication date: January 22, 2015
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kathie Kionisio
  • Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue of bone
    Patent number: 8802122
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: August 12, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kathie Dionisio
  • Fully synthetic implantable multi-phased scaffold
    Patent number: 8753391
    Abstract: An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: June 17, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Helen H. Lu, Jeffrey Spalazzi
  • NON-INVASIVE SUTURE ANCHOR AND METHOD
    Publication number: 20130238027
    Abstract: A non-invasive device for anchoring a suture includes a sheet to which a suture can be attached and an adhesive that can affix the sheet to bone. The method provides placing effective amount of an adhesive on a bone and attaching the suture to the adhesive and allowing the adhesive to set.
    Type: Application
    Filed: November 16, 2011
    Publication date: September 12, 2013
    Inventors: Renwen Zhang, Twana Davisson, Jeffrey Spalazzi, Venkat R. Garigapan, Anthony P. Nanpolitano
  • Biomimmetic nanofiber scaffold for soft tissue and soft tissue-to-bone repair, augmentation and replacement
    Publication number: 20110066242
    Abstract: An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering.
    Type: Application
    Filed: August 24, 2010
    Publication date: March 17, 2011
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kristen L. Moffat, William N. Levine
  • Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue of bone
    Publication number: 20100291178
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Application
    Filed: December 22, 2009
    Publication date: November 18, 2010
    Applicant: The Trustees of Columbia University
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kathie Dionisio
  • Fully synthetic implantable multi-phased scaffold
    Publication number: 20100292791
    Abstract: An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also provided is a fully synthetic implantable multiphased scaffold which includes, in a single continuous construct, a plurality of phases to mimic the natural anatomy of a tendon or ligament and their insertion sites. Also provided are scaffold apparatuses for musculoskeletal tissue engineering.
    Type: Application
    Filed: August 12, 2009
    Publication date: November 18, 2010
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kristen L. Moffat, William N. Levine
  • Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
    Patent number: 7767221
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: August 3, 2010
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Helen H. Lu, Jeffrey Spalazzi, Kathie Dionisio
  • Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
    Publication number: 20060067969
    Abstract: Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
    Type: Application
    Filed: March 4, 2005
    Publication date: March 30, 2006
    Inventors: Helen Lu, Jeffrey Spalazzi, Kathie Dionisio