Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.

Abstract: This invention is directed to a continuously cleanable, high performance filtration apparatus and a method for using the apparatus. The apparatus is a radial inflow centrifugal filtration device, which includes a filter element located within a chamber and rotatably coupled to a filtered fluid outlet in a bulkhead that abuts the chamber. The filter element is generally tubular, its side-walls encircling and, thus, defining an interior plenum. The filter element side-walls incorporate a filter media, preferably a laminated microporous membrane filter media. The filter element is rotatably coupled at the filtered fluid outlet by a seal which can maintain a seal as filter element rotates. Additionally, the device can include a boundary layer momentum transfer device made up of a plurality of stacked annular disks having central openings, each disk separated from adjacent disks by a desired gap. The central openings define a cavity in which the filter element is mounted.