Patents by Inventor Jeffrey T. Kreulen

Jeffrey T. Kreulen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10607720
    Abstract: The present invention relates to a method and system for associating gene expression data with a disease name. A first data set associated with a plurality of genetic probes for a plurality of biological samples may be received. The first data set may be sorted based on a normalized gene expression values for the plurality of genetic probes. A largest value gap of the normalized gene expression values may be identified. A set of expressed genes within the first data set may be identified. An indexable document may be generated for a biological sample of the plurality of biological samples comprising data associated with the set of expressed genes. A second data set associated with an expressed gene of the set of expressed genes may be searched. A disease name may be associated with an expressed gene based on a threshold correlation between the disease name and the expressed gene.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: March 31, 2020
    Assignee: International Business Machines Corporation
    Inventors: Linda H. Kato, Jeffrey T. Kreulen, Jacques Labrie, William S. Spangler, Ignacio G. Terrizzano
  • Publication number: 20190385706
    Abstract: The present invention relates to a method and system for associating gene expression data with a disease name. A first data set associated with a plurality of genetic probes for a plurality of biological samples may be received. The first data set may be sorted based on a normalized gene expression values for the plurality of genetic probes. A largest value gap of the normalized gene expression values may be identified. A set of expressed genes within the first data set may be identified. An indexable document may be generated for a biological sample of the plurality of biological samples comprising data associated with the set of expressed genes. A second data set associated with an expressed gene of the set of expressed genes may be searched. A disease name may be associated with an expressed gene based on a threshold correlation between the disease name and the expressed gene.
    Type: Application
    Filed: August 27, 2019
    Publication date: December 19, 2019
    Inventors: Linda H. Kato, Jeffrey T. Kreulen, Jacques Labrie, William S. Spangler, Ignacio G. Terrizzano
  • Publication number: 20170329900
    Abstract: The present invention relates to a method and system for associating gene expression data with a disease name. A first data set associated with a plurality of genetic probes for a plurality of biological samples may be received. The first data set may be sorted based on a normalized gene expression values for the plurality of genetic probes. A largest value gap of the normalized gene expression values may be identified. A set of expressed genes within the first data set may be identified. An indexable document may be generated for a biological sample of the plurality of biological samples comprising data associated with the set of expressed genes. A second data set associated with an expressed gene of the set of expressed genes may be searched. A disease name may be associated with an expressed gene based on a threshold correlation between the disease name and the expressed gene.
    Type: Application
    Filed: May 11, 2016
    Publication date: November 16, 2017
    Inventors: Linda H. Kato, Jeffrey T. Kreulen, Jacques Labrie, William S. Spangler, Ignacio G. Terrizzano
  • Patent number: 9495349
    Abstract: A system and method for processing a document to generate a set of related documents. A system is provided that includes a textual analytics system that analyzes unstructured data contained in a source document and extracts a set of structured information about the source document; and a compare system that identifies a set of related documents by comparing the set of structured information with metadata indexed from a set of publications.
    Type: Grant
    Filed: November 17, 2005
    Date of Patent: November 15, 2016
    Assignee: International Business Machines Corporation
    Inventors: Robert L. Angell, Stephen K. Boyer, James W. Cooper, Richard A. Hennessy, Tapas Kanungo, Jeffrey T. Kreulen, David C. Martin, James J. Rhodes, W. Scott Spangler, Herschel J. R. Weintraub
  • Publication number: 20150220680
    Abstract: A biological pathway is a series of actions that take place in an organism that lead to some resulting pathology or otherwise change the organism state. In the cell, these actions typically take place between molecules called proteins. Proteins within the cell interact in ways that are not fully understood, but evidence concerning these interactions is constantly being collected and published by microbiologists. The disclosed method automatically infers such biological pathways between proteins by looking at the overall system of published literature about those proteins.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 6, 2015
    Applicant: International Business Machines Corporation
    Inventors: STEPHEN K BOYER, JEFFREY T KREULEN, W SCOTT SPANGLER
  • Patent number: 8086644
    Abstract: Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: December 27, 2011
    Assignee: International Business Machines Corporation
    Inventors: Stephen K. Boyer, Kenneth M. Johns, Jeffrey T. Kreulen, James J. Rhodes, Hovey R. Strong, Jr.
  • Patent number: 7822704
    Abstract: A method and structure for analyzing a database having non-text data in data fields and text in text fields. The invention first selects a subset of the database based upon criteria. The subset includes data field(s) and associated text field(s). The invention searches for data matching the criteria within structured data fields of the database. If the invention searches multiple databases, the invention creates shared dimensions for databases that do not share common attributes. The invention automatically selects a relatively short text phrase from the text fields that helps to explain the underlying meaning (i.e. unique text content) of a data subset selected using the non-text data fields.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: October 26, 2010
    Assignee: International Business Machines Corporation
    Inventors: William F. Cody, Vikas Krishna, Justin T. Lessler, William S. Spangler, Jeffrey T. Kreulen
  • Patent number: 7805445
    Abstract: Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: September 28, 2010
    Assignee: International Business Machines Corporation
    Inventors: Stephen K. Boyer, Kenneth M. Johns, Jeffrey T. Kreulen, James J. Rhodes, Hovey R. Strong, Jr.
  • Publication number: 20100011192
    Abstract: Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source.
    Type: Application
    Filed: July 10, 2008
    Publication date: January 14, 2010
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen K. Boyer, Kenneth M. Johns, Jeffrey T. Kreulen, James J. Rhodes, Hovey R. Strong, JR.
  • Publication number: 20100011015
    Abstract: Methods, systems and computer program products for simplifying complex data stream problems involving feature extraction from noisy data. Exemplary embodiments include a method for processing a data stream, including applying multiple operators to the data stream, wherein an operation by each of the multiple operators includes retrieving the next chunk for each of set of input parameters, performing digital processing operations on a respective next chunk, producing sets of output parameters and adding data to one or more internal data stores, each internal data store acting as a data stream source.
    Type: Application
    Filed: July 11, 2008
    Publication date: January 14, 2010
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen K. Boyer, Kenneth M. Johns, Jeffrey T. Kreulen, James J. Rhodes, Hovey R. Strong, Jr.
  • Patent number: 7383257
    Abstract: A method and structure for analyzing a database having non-text data in data fields and text in text fields. The invention first selects a subset of the database based upon criteria. The subset includes data field(s) and associated text field(s). The invention searches for data matching the criteria within structured data fields of the database. If the invention searches multiple databases, the invention creates shared dimensions for databases that do not share common attributes. The invention automatically selects a relatively short text phrase from the text fields that helps to explain the underlying meaning (i.e. unique text content) of a data subset selected using the non-text data fields.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: June 3, 2008
    Assignee: International Business Machines Corporation
    Inventors: William F Cody, Vikas Krishna, Justin T. Lessler, William S Spangler, Jeffrey T. Kreulen
  • Publication number: 20040243561
    Abstract: A method and structure for analyzing a database having non-text data in data fields and text in text fields. The invention first selects a subset of the database based upon criteria. The subset includes data field(s) and associated text field(s). The invention searches for data matching the criteria within structured data fields of the database. If the invention searches multiple databases, the invention creates shared dimensions for databases that do not share common attributes. The invention automatically selects a relatively short text phrase from the text fields that helps to explain the underlying meaning (i.e. unique text content) of a data subset selected using the non-text data fields.
    Type: Application
    Filed: May 30, 2003
    Publication date: December 2, 2004
    Inventors: William F. Cody, Vikas Krishna, Justin T. Lessler, William S. Spangler, Jeffrey T. Kreulen
  • Patent number: 6725217
    Abstract: A computing system and method explores a knowledge repository by accepting a natural language query from a user, determining a distance between the query and every category in every partitioning of the knowledge repository, and displaying a radial graph (322) of the nearest categories. Further, in response to a user selecting a category, visually displaying matching elements in the category along with its nearest neighbor categories in a scatter plot (324).
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: April 20, 2004
    Assignee: International Business Machines Corporation
    Inventors: Amy W. Chow, Jeffrey T. Kreulen, Justin T. Lessler, Larry L. Proctor, W. Scott Spangler
  • Publication number: 20030004932
    Abstract: A computing system and method explores a knowledge repository by accepting a natural language query from a user, determining a distance between the query and every category in every partitioning of the knowledge repository, and displaying a radial graph (322) of the nearest categories. Further, in response to a user selecting a category, visually displaying matching elements in the category along with its nearest neighbor categories in a scatter plot (324).
    Type: Application
    Filed: June 20, 2001
    Publication date: January 2, 2003
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Amy W. Chow, Jeffrey T. Kreulen, Justin T. Lessler, Larry L. Proctor, W. Scott Spangler