Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.

Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.

Abstract: An identity and access management (IAM) system is associated with a set of data sources from which data is collected. A set of vulnerabilities that the IAM system should attempt to detect is identified. For each vulnerability to be detected, a prioritized list of strategies used to detect that vulnerability is generated. Preferably, each strategy specifies the type(s) of data required to detect that vulnerability. An algorithm to determine a best strategy to be used for detecting each vulnerability, preferably based on the data available from the data sources, is then identified. The IAM system then collects data in an optimized manner. In particular, during the collection process, the IAM system preferably collects only what is necessary based on the configuration, even if the data source is capable of providing additional data. The collected data is then processed to detect security vulnerabilities associated with the IAM accounts.

Abstract: An identity and access management (IAM) system is associated with a set of data sources from which data is collected. A set of vulnerabilities that the IAM system should attempt to detect is identified. For each vulnerability to be detected, a prioritized list of strategies used to detect that vulnerability is generated. Preferably, each strategy specifies the type(s) of data required to detect that vulnerability. An algorithm to determine a best strategy to be used for detecting each vulnerability, preferably based on the data available from the data sources, is then identified. The IAM system then collects data in an optimized manner. In particular, during the collection process, the IAM system preferably collects only what is necessary based on the configuration, even if the data source is capable of providing additional data. The collected data is then processed to detect security vulnerabilities associated with the IAM accounts.

Abstract: An identity and access management (IAM) system is associated with a set of data sources from which data is collected. A set of vulnerabilities that the IAM system should attempt to detect is identified. For each vulnerability to be detected, a prioritized list of strategies used to detect that vulnerability is generated. Preferably, each strategy specifies the type(s) of data required to detect that vulnerability. An algorithm to determine a best strategy to be used for detecting each vulnerability, preferably based on the data available from the data sources, is then identified. The IAM system then collects data in an optimized manner. In particular, during the collection process, the IAM system preferably collects only what is necessary based on the configuration, even if the data source is capable of providing additional data. The collected data is then processed to detect security vulnerabilities associated with the IAM accounts.

Abstract: A method for assessing security risks associated with a cloud application to which one or more connected applications are coupled begins by configuring a security risk assessment application to function as a connected application. The security risk assessment application collects “first” data associated with one or more accounts, and “second” data associated with the one or more connected applications coupled to the cloud application. After receiving the first and second data, the security risk assessment application instantiates that data into a generic “data object” that the system uses to represent each account and each of the connected applications. Each such data object thus is populated either with the first data or the second data, depending on whether the data object represents an account or a connected application. A risk assessment is then applied to the generic data object to assess a security risk associated with the cloud application.

Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.

Abstract: An identity management system is augmented to enable a manager to associate “risk” metadata with different types of access requests representing computer system accounts that can be requested by authorized users. When an authorized user then requests access to a particular account, any “risk” associated with that access is shown to the user, typically in the form of a visual “badge” or other such indicator. The badge includes an appropriate informational display (e.g., “High Risk” or “Regulated”) that provides an appropriate risk warning. The risk metadata badge information preferably also is displayed for risk-based access request approval routing; in such context, the risk metadata may also determine the risk approval workflow itself. Thus, for example, if the risk metadata is present when the authorized user requests access, an approval workflow may be modified so that the request approval is routed appropriately.

Abstract: An identity management system is augmented to enable a manager to associate “risk” metadata with different types of access requests representing computer system accounts that can be requested by authorized users. When an authorized user then requests access to a particular account, any “risk” associated with that access is shown to the user, typically in the form of a visual “badge” or other such indicator. The badge includes an appropriate informational display (e.g., “High Risk” or “Regulated”) that provides an appropriate risk warning. The risk metadata badge information preferably also is displayed for risk-based access request approval routing; in such context, the risk metadata may also determine the risk approval workflow itself. Thus, for example, if the risk metadata is present when the authorized user requests access, an approval workflow may be modified so that the request approval is routed appropriately.

Abstract: A method, system, and computer usable program product for automated document governance in a data processing environment are provided in the illustrative embodiments. A set of structured documents is received at an application executing in a computer in the data processing environment. A structure is recognized, parts of which structure are present in the documents in the set. A set of similarities in the documents in the set is summarized according to the recognized structure. A summarized information from the summarizing is presented such that a document governance action can be performed on a subset of the set of documents using the summarized information.

Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.