Abstract: A medical device comprises a handle including an actuator, a shaft extending distally from the handle, wherein the shaft includes a lumen, and a distal cap. The distal cap includes a body including a first channel, wherein the first channel is in communication with a distal portion of the lumen, a distal face including an opening, wherein the opening is a distal opening of the channel, and an expandable portion coupled to the body, wherein the expandable portion is configured to expand radially outwards from the body and to retract radially inwards towards the body from an expanded position. The expandable portion includes at least one light.

Abstract: An apparatus for delivering a powdered agent into a subject's body may include a first passage for receiving a pressurized gas. The apparatus also may include a container housing a powdered agent. The container may be in fluid connection with the first passage. At least a portion of the pressurized gas is introduced into the powdered agent in the container to fluidize the powdered agent. The apparatus also may include a second passage for receiving the powdered agent from the container. In a first configuration of the apparatus, the second passage may not be in fluid connection with the container. In a second configuration of the apparatus, the second passage may be in fluid connection with the container. The apparatus may be configured to transition between the first configuration and the second configuration.

Abstract: An apparatus for delivering a powdered agent into a subject's body may include a first passage for receiving a pressurized gas. The apparatus also may include a container housing a powdered agent. The container may be in fluid connection with the first passage. At least a portion of the pressurized gas is introduced into the powdered agent in the container to fluidize the powdered agent. The apparatus also may include a second passage for receiving the powdered agent from the container. In a first configuration of the apparatus, the second passage may not be in fluid connection with the container. In a second configuration of the apparatus, the second passage may be in fluid connection with the container. The apparatus may be configured to transition between the first configuration and the second configuration.

Abstract: A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device.

Abstract: A biopsy device may include a first jaw having a first distal tip configured to pierce tissue, and a second jaw movable relative to the first jaw between a closed configuration where the first jaw and the second jaw are axially aligned, and an open configuration where the first jaw and the second jaw are offset from one another, the second jaw having a second distal tip proximal to the first distal tip in the closed configuration.

Abstract: A biopsy device may include a first jaw having a first distal tip configured to pierce tissue, and a second jaw movable relative to the first jaw between a closed configuration where the first jaw and the second jaw are axially aligned, and an open configuration where the first jaw and the second jaw are offset from one another, the second jaw having a second distal tip proximal to the first distal tip in the closed configuration.

Abstract: According to exemplary embodiments of the present disclosure, devices, systems, and methods for endoscopic procedures may include an end effector of a grasping system having a first arm and a second arm. The first and second arms may extend from a common proximal joint. The first and second arms may be formed of a self-expanding material and may have a spring force to set the arms in an unconstrained open position. The first and second arms may have an arc shape such that a distal tip of each first and second arm are configured to close as the first and second arms are actuated to a constrained closed position. A catheter may include a locating element at a distal end of a flexible tube. The locating element may be configured for locating the grasping system.

Abstract: An apparatus for delivering a powdered agent into a subject's body may include a first passage for receiving a pressurized gas. The apparatus also may include a container housing a powdered agent. The container may be in fluid connection with the first passage. At least a portion of the pressurized gas is introduced into the powdered agent in the container to fluidize the powdered agent. The apparatus also may include a second passage for receiving the powdered agent from the container. In a first configuration of the apparatus, the second passage may not be in fluid connection with the container. In a second configuration of the apparatus, the second passage may be in fluid connection with the container. The apparatus may be configured to transition between the first configuration and the second configuration.

Abstract: A biopsy device may include a first jaw having a first distal tip configured to pierce tissue, and a second jaw movable relative to the first jaw between a closed configuration where the first jaw and the second jaw are axially aligned, and an open configuration where the first jaw and the second jaw are offset from one another, the second jaw having a second distal tip proximal to the first distal tip in the closed configuration.

Abstract: A stent loading and delivery system, the delivery system comprising an inner elongate tubular member having a proximal end and a distal end, an intermediate elongate tubular member having a proximal end and a distal end in sliding relationship to said inner elongate tubular member and an external elongate tubular member having a proximal end and a distal end in sliding relationship to said intermediate elongate tubular member, said intermediate elongate tubular member comprising a stop mechanism at its proximal end, wherein the stop mechanism prevents the external elongate tubular member from being slid past the stop mechanism when the external elongate tubular member is slid in a proximal direction.

Abstract: A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device.

Abstract: A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device.

Abstract: A stent loading and delivery system, the delivery system comprising an inner elongate tubular member having a proximal end and a distal end, an intermediate elongate tubular member having a proximal end and a distal end in sliding relationship to said inner elongate tubular member and an external elongate tubular member having a proximal end and a distal end in sliding relationship to said intermediate elongate tubular member, said intermediate elongate tubular member comprising a stop mechanism at its proximal end, wherein the stop mechanism prevents the external elongate tubular member from being slid past the stop mechanism when the external elongate tubular member is slid in a proximal direction.

Abstract: A stent loading and delivery system, the delivery system comprising an inner elongate tubular member having a proximal end and a distal end, an intermediate elongate tubular member having a proximal end and a distal end in sliding relationship to said inner elongate tubular member and an external elongate tubular member having a proximal end and a distal end in sliding relationship to said intermediate elongate tubular member, said intermediate elongate tubular member comprising a stop mechanism at its proximal end, wherein the stop mechanism prevents the external elongate tubular member from being slid past the stop mechanism when the external elongate tubular member is slid in a proximal direction.

Abstract: A stent loading and delivery system, the delivery system comprising an inner elongate tubular member having a proximal end and a distal end, an intermediate elongate tubular member having a proximal end and a distal end in sliding relationship to said inner elongate tubular member and an external elongate tubular member having a proximal end and a distal end in sliding relationship to said intermediate elongate tubular member, said intermediate elongate tubular member comprising a stop mechanism at its proximal end, wherein the stop mechanism prevents the external elongate tubular member from being slid past the stop mechanism when the external elongate tubular member is slid in a proximal direction.

Abstract: A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device.

Abstract: A method of treating a tissue region (e.g., a tumor) is provided. The method comprises introducing a delivery sheath within an anatomical conduit that supplies the tissue region with a fluid (e.g., blood or air). The anatomical conduit may be any naturally occurring conduit within a patient. The method further comprises expanding an occlusive device (e.g., a balloon) associated with the delivery sheath, such that the conduit is at least partially occluded to reduce the flow of fluid through the conduit. The method further comprises introducing a tissue treatment catheter within the delivery sheath, advancing the treatment catheter from the delivery sheath through an aperture in a wall of the conduit adjacent the tissue region, and conveying thermal energy from (i.e., hyperthermia) or to the treatment catheter (i.e., hypothermia) to treat (e.g., by ablating) the tissue region.

Abstract: A tissue constrictor includes one or more shape-changing materials that when activated aids in constricting a portion of an organ or tissue in the body. In one embodiment, the constrictor conducts electrosurgical or ablation energy to section tissue.

Abstract: A method of treating a tissue region (e.g., a tumor) is provided. The method comprises introducing a delivery sheath within an anatomical conduit that supplies the tissue region with a fluid (e.g., blood or air). The anatomical conduit may be any naturally occurring conduit within a patient. The method further comprises expanding an occlusive device (e.g., a balloon) associated with the delivery sheath, such that the conduit is at least partially occluded to reduce the flow of fluid through the conduit. The method further comprises introducing a tissue treatment catheter within the delivery sheath, advancing the treatment catheter from the delivery sheath through an aperture in a wall of the conduit adjacent the tissue region, and conveying thermal energy from (i.e., hyperthermia) or to the treatment catheter (i.e., hypothermia) to treat (e.g., by ablating) the tissue region.

Abstract: The present invention is a method and apparatus for interconnection system. A first front connector is located at a side of a first front card to provide first contacts for first signal traces on the first front card. A second front connector located at a side of a second front card to provide second contacts for second signal traces on the second front card. A mating connector has first and second receptacles and is located alongside of a rear card. The mating connector electrically connects the first contacts of the first signal traces to the second contacts of the second signal traces via contacts in the first and second receptacles. The first and second receptacles couple to the first and second front connectors, respectively. The rear card is positioned in a substantially orthogonal direction to the first and second front cards.