Abstract: Compositions for hair treatment comprising discrete droplets which contain both a functionalised silicone and a hydrocarbon oil, methods for preparing such compositions and their use for conditioning of hair.

Abstract: Methods are disclosed for entrapment of a cation in a vesicle having a membrane and an acidic aqueous compartment comprising contacting the vesicle with a buffer solution comprising the cation and a lipophilic, carboxylic ionophoretic antibiotic capable of complexing with the cation and increasing the cation's permeability across the vesicle membrane, wherein there is a pH gradient between the acidic aqueous compartment and the buffer solution. The cation can be for example iron or calcium and the ionophore A23187. The pH gradient can be established across the bilayer by a relatively acidic or basic intravesicular aqueous compartment of the unilamellar vesicle and the buffer solution and the cation loads via the pH gradient. The invention also contemplates a unilamellar vesicle comprising an aqueous compartment including a cationic species in a concentration between 100 mM and 500 mM.