Patents by Inventor Jeffrey W. Corbett

Jeffrey W. Corbett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6599916
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 29, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Substituted 7-aza[2.2.1]bicycloheptanes for the treatment of disease
    Publication number: 20030105089
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: September 4, 2002
    Publication date: June 5, 2003
    Inventors: Donn G. Wishka, Daniel Patrick Walker, Jeffrey W. Corbett, Steven Charles Reitz, Mark R. Rauckhorst, Vincent E. Groppi
  • 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolines useful as HIV reverse transcriptase inhibitors
    Publication number: 20030092722
    Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: 1
    Type: Application
    Filed: June 11, 2002
    Publication date: May 15, 2003
    Inventors: Jeffrey W. Corbett, Soo S. Ko
  • Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
    Patent number: 6562816
    Abstract: The invention provides compounds of Formula I: compounds of the Formula I: wherein R1, R2, R4, R6, X, and W are defined herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: May 13, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Donn G. Wishka, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, David W. Piotrowski, Jeffrey W. Corbett, Alice L. Bodnar, Vincent E. Groppi, Jr.
  • Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Publication number: 20030073707
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 6, 2002
    Publication date: April 17, 2003
    Inventors: Daniel Patrick Walker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, David W. Piotrowski, Vincent E. Groppi
  • SUBSTITUTED-HETEROARYL-7-AZA[2.2.1] BYCYCLOHEPTANES FOR THE TREATMENT OF DESEASE
    Publication number: 20030069290
    Abstract: The invention provides compounds of Formula I: compounds of the Formula I: 1
    Type: Application
    Filed: August 14, 2002
    Publication date: April 10, 2003
    Inventors: Donn G. Wishka, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, David W. Piotrowski, Jeffrey W. Corbett, Alice L. Bodnar, Vincent E. Groppi,
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6500840
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 31, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6492385
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 10, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones useful as HIV reverse transcriptase inhibitors
    Patent number: 6423718
    Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: July 23, 2002
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Jeffrey W. Corbett, Soo S. Ko
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020091135
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: July 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi,, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020042429
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: April 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020042428
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: April 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi,, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinthiones useful as HIV reverse transcriptase inhibitors
    Patent number: 6127375
    Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinthiones of formula I: ##STR1## or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: October 3, 2000
    Assignee: Dupont Pharmaceuticals Company
    Inventor: Jeffrey W. Corbett
  • 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones useful as HIV reverse transcriptase inhibitors
    Patent number: 6124302
    Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones of formula I: ##STR1## or steroisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent, wherein:R.sup.1 is C.sub.1-3 alkyl substituted with 1-7 halogen;R.sup.2 is optionally substituted C.sub.1-5 alkyl, optionally substituted C.sub.2-5 alkenyl, or optionally substituted C.sub.2-5 alkynyl;R.sup.3, at each occurrence, is independently selected from C.sub.1-4 alkyl, OH, C.sub.1-4 alkoxy, F, Cl, Br, I, NR.sup.5 R.sup.5a, NO.sub.2, CN, C(O)R.sup.6, NHC(O)R.sup.7, and NHC(O)NR.sup.5 R.sup.5a ;R.sup.5 and R.sup.5a are independently selected from H and C.sub.1-3 alkyl;R.sup.6 is selected from H, OH, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, and NR.sup.5 R.sup.5a ;R.sup.
    Type: Grant
    Filed: April 8, 1998
    Date of Patent: September 26, 2000
    Assignee: DuPont Pharmaceuticals
    Inventors: Jeffrey W. Corbett, Soo S. Ko