Abstract: An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.

Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed. The bendable tip can include a pliable material possessing a treatment characteristic of being bendable by a user three or more times without kinking from a generally straight orientation to a self-supporting bent configuration spanning an angle of at least forty degrees while remaining fully operational.

Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed.

Abstract: A system and method for rapidly responding to and regaining control of uncontrolled flow from offshore hydrocarbon wells, that includes a subsea containment assembly, optionally including a capture caisson assembly installed around the assembly, riser systems for production of hydrocarbons to capture vessels on the surface of the sea, and modularized subsystems facilitating communication between and fluid flow from the subsea containment assembly through the riser to the capture vessel.

Abstract: A system and method for rapidly responding to and regaining control of uncontrolled flow from offshore hydrocarbon wells, comprising a subsea containment assembly, optionally including a capture caisson assembly installed around the assembly, riser systems for production of hydrocarbons to capture vessels on the surface of the sea, and modularized subsystems facilitating communication between and fluid flow from the subsea containment assembly through the riser to the capture vessel.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal and other manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: A radiation emitting apparatus is disclosed that emits a substantially homogenous beam of radiation from an irregularly shaped output end. As described herein, a radiation emitting apparatus includes a bundled fiber guide coupled to an energy distribution tuner. The bundled fiber guide is coupled to the energy distribution tuner to receive a substantially uniform distribution of high power energy. The bundled fiber guide is configured to distribute the energy to emit a substantially uniform distribution of lower power energy toward a target surface, such as a body surface. The bundled fiber guide may include a plurality of fused optic fibers, a plurality of beam splitting mirror elements, or tapered waveguides.

Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed.

Abstract: An apparatus is used to perform disinfection procedures on target tissues within root canal passages and tubules. The apparatus can include an electromagnetic radiation emitting tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the apparatus can include a porous structure that encompasses a region of the tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues. Another aspect can include provision of the apparatus with an adjustable channel-depth indicator, which encompasses a region of the tip besides the radiation emitting region and which is movable in proximal and distal directions along a surface of the tip to facilitate the provision of depth-of-insertion information to users of the apparatus.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: Mouthpieces having activated textured surfaces that can be implemented using repetitive movement mechanisms and energy (e.g., electromagnetic radiation) emitting sources are disclosed. The mouthpieces may be used to provide detection, treatment and management of conditions including tooth discoloration and periodontal disease. Implementations can include a low-profile mouthpiece or a mouthpiece covering only front sides of the upper and lower teeth. Other combinations may include full-mouth implementations suitable for simultaneously covering part or all of a patient's upper and lower rows of teeth. The activated textured surfaces may include a surface topography consisting of bristles.

Abstract: An endodontic probe is used to perform disinfection procedures on target tissues within root canal passages and tubules. The endodontic probe can include an electromagnetic radiation emitting fiber optic tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the endodontic probe can include a porous structure that encompasses a region of the fiber optic tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues.

Abstract: A laser handpiece is disclosed, including a shaped fiber optic tip having a side-firing output end with a double bevel-cut shape. The shaped fiber optic tip can be configured to side-fire laser energy in a direction away from a laser handpiece and toward sidewalls of a treatment or target site.

Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed.

Abstract: A system and method for rapidly responding to and regaining control of uncontrolled flow from offshore hydrocarbon wells, comprising a subsea containment assembly, optionally including a capture caisson assembly installed around the assembly, riser systems for production of hydrocarbons to capture vessels on the surface of the sea, and modularized subsystems facilitating communication between and fluid flow from the subsea containment assembly through the riser to the capture vessel.

Abstract: A radiation emitting apparatus is disclosed that emits a substantially homogenous beam of radiation from an irregularly shaped output end. As described herein, a radiation emitting apparatus includes a bundled fiber guide coupled to an energy distribution tuner. The bundled fiber guide is coupled to the energy distribution tuner to receive a substantially uniform distribution of high power energy. The bundled fiber guide is configured to distribute the energy to emit a substantially uniform distribution of lower power energy toward a target surface, such as a body surface. The bundled fiber guide may include a plurality of fused optic fibers, a plurality of beam splitting mirror elements, or tapered waveguides.

Abstract: An endodontic probe is used to perform disinfection procedures on target tissues within root canal passages and tubules. The endodontic probe can include an electromagnetic radiation emitting fiber optic tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the endodontic probe can include a porous structure that encompasses a region of the fiber optic tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues.