Abstract: A product configuration device outputs a configuration of a product in accordance with a set of configuration rules. The product configuration device includes a rule learning system configured to acquire a first set of data representing a plurality of configurations of the product; to generate a neural network model representing the first set of data; to extract relationships between configuration attributes from the neural network model; and to modify the set of configuration rules based on the extracted relationships to generate a modified set of configuration rules for the product configuration device. The product configuration device may also include a rule execution engine that outputs the configuration of the product based on the modified set of configuration rules.

Abstract: An HVAC system is provided. Embodiments of the present disclosure generally relate to HVAC systems in communication with a test engine configured to schedule maintenance and service calls. In one embodiment the test engine utilizes the ambient temperature and temperature setpoint to establish a maintenance schedule.

Abstract: An HVAC system is provided. Embodiments of the present disclosure generally relate to HVAC systems in communication with a test engine configured to schedule maintenance and service calls. In one embodiment the test engine utilizes the ambient temperature and temperature setpoint to establish a maintenance schedule.

Abstract: The present disclosure relates to methods of treating adult-onset Still’s disease (AOSD) or systemic-onset juvenile idiopathic arthritis (SoJIA), optionally associated with elevated IL-18 levels, comprising administering to a human subject diagnosed with AOSD or SoJIA an effective amount of an anti-IL-18 antibody at certain dosages.

Abstract: Embodiments operate a configurator that generates a quote for a product or service configuration, the quote including a quote workflow that includes at least one required quote approval and the quote includes a plurality of quote attributes that define the quote. Embodiments input the plurality of quote attributes into a first neural network model and a second neural network model and generate with a gradient descent a likelihood that the quote will be approved and a time required for the quote to be approved. Embodiments generate one or more attributes with the largest gradient values for the likelihood that the quote will be approved and the time required for the quote to be approved. Embodiments receive a change to one or more of the attributes and regenerate the likelihood that the quote will be approved and/or the time required for the quote to be approved based on the change.

Abstract: Systems and methods for computer-implemented pre-optimization of input data before further processing thereof by a computer-implemented analyzation process, such as optical character recognition (OCR). A cooperative model is employed that combines one or more supervised-learning based inspector sub-models, and one or more filter sub-models that operating in series with the inspector sub-model(s). The inspectors first receive the input data and calculate one predicted transformation parameters then used to perform transformations on the input data. The inspector-transformed data is then passed to the filters, which derive respective convolution kernels and apply same to the inspector-transformed data before passing same to the OCR or other analyzation process. The inspectors may be pretrained with different training data.

Abstract: An HVAC system is provided. Embodiments of the present disclosure generally relate to HVAC systems in communication with a test engine configured to schedule maintenance and service calls. In one embodiment the test engine utilizes the ambient temperature and temperature setpoint to establish a maintenance schedule.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.

Abstract: The invention provides methods for treating a cancer selected from the group consisting of (i) a squamous cell carcinoma located in a patient's head and/or neck and (ii) a urothelial carcinoma using aryl dihydro-2H-benzo[b][1,4]oxazine sulfonamide compounds.

Abstract: Embodiments operate a configurator that generates a quote for a product or service configuration, the quote including a quote workflow that includes at least one required quote approval and the quote includes a plurality of quote attributes that define the quote. Embodiments input the plurality of quote attributes into a first neural network model and a second neural network model and generate with a gradient descent a likelihood that the quote will be approved and a time required for the quote to be approved. Embodiments generate one or more attributes with the largest gradient values for the likelihood that the quote will be approved and the time required for the quote to be approved. Embodiments receive a change to one or more of the attributes and regenerate the likelihood that the quote will be approved and/or the time required for the quote to be approved based on the change.

Abstract: A product configuration device outputs a configuration of a product in accordance with a set of configuration rules. The product configuration device includes a rule learning system configured to acquire a first set of data representing a plurality of configurations of the product; to generate a neural network model representing the first set of data; to extract relationships between configuration attributes from the neural network model; and to modify the set of configuration rules based on the extracted relationships to generate a modified set of configuration rules for the product configuration device. The product configuration device may also include a rule execution engine that outputs the configuration of the product based on the modified set of configuration rules.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.

Abstract: Embodiments relate to pharmaceutical compositions, comprising one or more beta-3 adrenoceptor agonists that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder, prostate disorders and methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising one or more beta-3 adrenoceptor agonists. In some embodiments, the pharmaceutical compositions, comprising one or more beta-3 adrenoceptor agonists comprise pulsatile drug delivery systems. Embodiments further relate to a dosing regimen, comprising beta-3 adrenoceptor agonists and anti-muscarinic agents that are both useful for the treatment of lower urinary tract symptoms; methods for treating lower urinary tract symptoms methods utilizing the dosing regimens, comprising beta-3 adrenoceptor agonists anti-muscarinic agents; and consumer packaging, comprising both beta-3 adrenoceptor agonists and anti-muscarinic agents packaged and arranged to ensure patient compliance.

Abstract: This application relates to pharmaceutical compositions, comprising solabegron that are useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to methods for treating lower urinary tract symptoms utilizing the pharmaceutical compositions, comprising solabegron. In some embodiments, the pharmaceutical compositions, comprising solabegron comprise a dual release drug delivery system.