Patents by Inventor Jeffrey William Strovel

Jeffrey William Strovel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule BET bromodomain inhibitors and uses thereof
    Patent number: 11028079
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: June 8, 2021
    Assignees: ConverGene, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Yang, Ajit Jadhav, Daniel Jason Urban
  • Methods and compositions for inhibition of bromodomain-containing proteins
    Patent number: 10717739
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: July 21, 2020
    Assignee: CONVERGENE LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • SMALL MOLECULE BET BROMODOMAIN INHIBITORS AND USES THEREOF
    Publication number: 20200223836
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: November 15, 2019
    Publication date: July 16, 2020
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Ming Yang, Ajit Jadhav, Daniel Jason Urban, JR.
  • Bicyclic BET bromodomain inhibitors and uses thereof
    Patent number: 10508106
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: December 17, 2019
    Assignees: ConverGene LLC, The United States of America, As Represented by the Secretary, Department of Health and Human Services
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Ming Yang, Ajit Jadhav, Daniel Jason Urban
  • Methods and Compositions for Inhibition of Bromodomain-Containing Proteins
    Publication number: 20190345162
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: April 16, 2019
    Publication date: November 14, 2019
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • Methods and Compositions for Inhibition of Bromodomain and Extratermial Proteins
    Publication number: 20190092761
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: November 13, 2015
    Publication date: March 28, 2019
    Inventors: Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • BICYCLIC BET BROMODOMAIN INHIBITORS AND USES THEREOF
    Publication number: 20180305344
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: November 23, 2016
    Publication date: October 25, 2018
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Ming Yang, Ajit Jadhav, Daniel Jason Urban
  • Methods and compositions for inhibition of bromodomain-containing proteins
    Patent number: 9695179
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: July 4, 2017
    Assignee: ConverGene LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • METHODS AND COMPOSITIONS FOR INHIBITION OF BROMODOMAIN-CONTAINING PROTEINS
    Publication number: 20160024096
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Applicant: CONVERGENE LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia