Abstract: The present disclosure relates to, among others, a composition comprising an internalization peptide, also called a cellular uptake peptide, connected to a drug product, also called a therapeutic payload, by a linker.

Abstract: The disclosure is directed to compositions that specifically bind to the Tim-4, and related methods of use.

Abstract: The present invention provides an expression vector, host cells, methods and kits for the treatment or prevention of a coronavirus infection in a subject.

Abstract: A package assembly for packaging a replacement mower blade is provided. The package assembly includes a blade hang tab removably attached to an end of a mower blade. A shrink film tube is positioned about the mower blade and blade hang tab, wherein the shrink film is heated to shrink the shrink film and secure the blade hang tab to the mower blade. In another embodiment, the package assembly includes multiple blades encased within shrink film with a blade hang tab attached to one of the blades within the shrink film.

Abstract: A package assembly for packaging a replacement mower blade is provided. The package assembly includes a blade hang tab removably attached to an end of a mower blade. A shrink film tube is positioned about the mower blade and blade hang tab, wherein the shrink film is heated to shrink the shrink film and secure the blade hang tab to the mower blade. In another embodiment, the package assembly includes multiple blades encased within shrink film with a blade hang tab attached to one of the blades within the shrink film.

Abstract: A method for effecting data communications with a wireless communication device includes: (a) configuring the wireless communication device for responding to at least one predetermined alert for initiating the data communications with at least one predetermined communicant; (b) transmitting the at least one predetermined alert to the wireless communication device; and (c) operating the wireless communication device in response to recognizing the at least one predetermined alert to initiate a data session for effecting the data communications with the at least one predetermined communicant.

Abstract: An enhanced messaging capability which enables the recipient of the message to respond to a query by pressing a single button or multiple buttons to issue the response. Code for enabling a receiving device to display the message and provide simplified response options is carried by a messaging format such as SMS, MMS, etc., in which a web browser application is not required nor invoked to permit active response functionality. A mechanism is provide to allow delivery of response in a variety of formats. The system may automatically take a selected action if a response is not received within a present time period. A message and response system greatly simplified from the senders and recipients perspective is provided.

Abstract: A system and method for use in remotely adjusting, activating, or reprogramming features of a wireless device by utilizing a web interface or portal, such as a computer connected by a network to a server, or by telephone access to an IVR menu on the server, is described. Upon recognition of the command, the server issues a short message service (SMS) message, GPRS message, Bluetooth transmission, WIFI transmission, JAVA, or other data signal, or other type of wireless instruction to the wireless device to modify the desired feature. Alternatively, the wireless device can be prompted by a predetermined caller ID number as a unique programming command to be implemented by the wireless device for adjustments to an operational feature.

Abstract: An enhanced messaging capability which enables the recipient of the message to respond to a query by pressing a single button or multiple buttons to issue the response. Code for enabling a receiving device to display the message and provide simplified response options is carried by a messaging format such as SMS, MMS, etc., in which a web browser application is not required nor invoked to permit active response functionality. A mechanism is provide to allow delivery of response in a variety of formats. The system may automatically take a selected action if a response is not received within a present time period. A message and response system greatly simplified from the senders and recipients perspective is provided.

Abstract: A light bulb (10) includes a translucent housing (12) and a base (24). The housing (12) includes a plurality of LEDs (14a, 14b, 14c, and 15) positioned so as to emit light through the housing (12). The base (24) is configured to mate with a light socket. The base (24) also includes a compartment (23) for receiving and securing a replaceable active ingredient cartridge (22), and an active ingredient dispenser (20) for emitting an active ingredient from the cartridge (22) when the cartridge (22) is secured in the compartment (23). A fluorescent light source (30) may also be provided in the housing (12) as a source of illumination.

Abstract: A light element includes a translucent shell and a base. The base supports a plurality of LEDs positioned so as to emit a light show through the shell. The device also includes a compartment for receiving and securing a placeable volatile active cartridge and a heater for enabling the device to effectively emit an active ingredient from the cartridge when the cartridge is secured in the compartment. A white light source is provided in the shell as a source of illumination along with the LEDs The device can be used as a white light source, for displaying a colored light show, for displaying colored light schemes and for volatile active emission The devise may include an acoustic transducer for producing light and sound show.

Abstract: A light element includes a decorative, patterned translucent outer shell and a base. The base supports a plurality of LEDs positioned so as to emit a light show through the shell. The device also includes a compartment for receiving and securing a replaceable volatile active cartridge and a heater for enabling the device to effectively emit an active ingredient from the cartridge when the cartridge is secured in the compartment A white light source is provided in the shell as a source of illumination along with the LEDs The device can be used as a white light source, for displaying a colored light show, for displaying colored light is schemes and for volatile active emission. The device may include an acoustic transducer for producing light and sound shows. The device may also include a light sensor, a motion detector and/or a microphone or acoustic receiver thereby enabling the light and sound show to be dependent upon ambient light intensity, motion detection and/or ambient noise.

Abstract: An outdoor light system comprising a plurality light elements linked to a central controller. Each light element include a translucent shell, plurality of LEDs positioned so as to emit a light show through the shell A compartment for receiving and securing a replaceable volatile active cartridge and a heater for enabling the device to effectively emit an active ingredient from the cartridge when the cartridge is secured in the compartment. A white light source may be provided in each device as a source of illumination along with the LEDs The devices can be used as white light sources, for displaying a coordinated colored light shows, for displaying colored light schemes and for volatile active emission. The devices of disclosed the system may include an acoustic transducer for producing light and sound shows.

Abstract: A replacement device for a light bulb includes a translucent shell and a base. The base supports a plurality of colored lights positioned so as to emit a light show through the shell. The base is configured to be received in a conventional light socket. The base also includes a compartment for receiving and securing a replaceable volatile active cartridge for enabling the device to emit an active ingredient from the cartridge when the cartridge is secured in the compartment. A dimmable white light source may also provided in the shell as a source of illumination. Thus, a single device is used as a replacement for a conventional light bulb and is a combination white light source/colored light show source/volatile active source.

Abstract: An apparatus for dispensing active materials comprises a housing and control circuitry disposed within the housing. The control circuitry implements programming for a mode of operation in which during a first period of time a first active material is emitted, during a second period of time the first active material and a second active material are emitted, and during a third period of time the second active material is emitted, wherein during the second period of time, the first and second fragrances are altered.

Abstract: A replacement device for a light bulb includes a translucent shell and a base. The base supports a plurality of LEDs positioned so as to emit a light show through the shell. The base is configured to be received in a conventional light socket. The base also includes a compartment for receiving and securing a replaceable volatile active cartridge and a heater for enabling the device to effectively emit an active ingredient from the cartridge when the cartridge is secured in the compartment. A white light source is also provided in the shell as a source of illumination. The device can be used as a white light source, for displaying a colored light show and for volatile active emission. The volatile active may be emitted continuously when the device is used as either a white light source or for purposes of displaying a colored light show. Thus, a single device is used as a replacement for a conventional light bulb and is a combination white light source/colored light show source/volatile active source.

Abstract: An Edison-style light bulb (40) which supports a plurality of light emitting diodes (LEDs) (50) and an illumination source (54). First and second electrical circuits (56) and (58) are mounted in the bulb to supply electrical power to the illumination source and to the LEDs. A switch circuit (60) is connected to control the supply of electrical power to the first and second electrical circuits (56) and (58) to adjust and coordinate the light output from the LEDs (50) and from the illumination source (54).

Abstract: An electrically operated diffuser has a fragrance-emitting element (8) for facilitating diffusion of an active material, and at least one light emitting diode (7). The at least one light emitting diode (7) serves as a nightlight and has a luminous intensity rating of at least about 5000 mcd at 20 mA. Also, the at least one light emitting diode (7) may be positioned at a back surface of the diffuser, such that when an active material is received in the compartment the at least one light emitting diode (7) shines through the active material. The diffuser may include a remote-use assembly to supply power to the diffuser from a wall socket remote from the diffuser. The diffuser may also include a light controller to change one or more of the color and the intensity of the at least one light emitting diode (7).

Abstract: A control for a multisensory apparatus comprises means for detecting a number of lights connected to the control. The control further includes means responsive to the detecting means for operating the light(s) connected to the control in either of first and second different modes of operation in dependence upon the detected number of lights connected thereto. Still further, the control includes means for actuating an active material dispenser.

Abstract: Upon request, a computer can provide a useful collection of medical coding data to another computer on a network. The collection can be tailored to a particular medical specialty. The collection can be provided in a printable form that relates the various code relationships which may be needed for accurate use of the codes. Various embodiments may provide a book with a separate page for each code that includes the fee for the code, codes that are mutually exclusive with the code, and codes that may be needed in addition to the code. Other useful information can also be associated with the codes provided in the collection. Appropriate fees for codes in the collection can be provided, which may need to be calculated for each medical services provider depending on variables such as a geographic location of the medical service provider.