Patents by Inventor Jeffrey XING

Jeffrey XING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Shearing and Tagging DNA for Chromatin Immunoprecipitation and Sequencing
    Publication number: 20160208323
    Abstract: Disclosed are methods for shearing and tagging chromatin DNA. The disclosed methods include contacting chromatin DNA with at least one transposome, that includes a transposase enzyme. The transposon is made up of a first DNA molecule that includes a first transposase recognition site and a second DNA molecule that includes a second transposase recognition site, wherein the transposase integrates the first and second DNA molecules into chromatin DNA. The first and second DNA molecules of the transposon can be disconnected, such that upon integration of the transposon the chromatin bound DNA is sheared and tagged with the first and second DNA molecules, for example to prepare a library of sheared and tagged chromatin DNA fragments.
    Type: Application
    Filed: June 19, 2014
    Publication date: July 21, 2016
    Inventors: Bradley BERNSTEIN, Alon GOREN, Chad NUSBAUM, Oren RAM, Assaf ROTEM, Daniel TARJAN, Jeffrey XING, Aviv REGEV