Patents by Inventor Jeffry A. Siegal

Jeffry A. Siegal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7668662
    Abstract: A patient-specific optimally effective radiation dose for administration of a radiopharmaceutical to a patient for treatment of a disease may be established by basing the calculation of the appropriate therapeutic dose on factors such as the desired total body dose, the maximum tolerated dose, the typical clearance profile of the radiopharmaceutical, the patient's mass or maximum effective mass, and the patient-specific residence time of the radiopharmaceutical or an analog in the whole body of the patient. The use of the method allows for treatment of a patient with an appropriate dose which is maximally effective against the disease yet minimally toxic. The determination of a patient-specific therapeutic dose may be assisted by the use of a software program set to the particular parameters of the radiopharmaceutical.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: February 23, 2010
    Assignees: The Regents of the University of Michigan, Smithkline Beecham Corporation
    Inventors: Stewart M. Kroll, Jeffry A. Siegal, Richard L. Wahl, Kenneth R. Zasadny
  • Publication number: 20050288869
    Abstract: A patient-specific optimally effective radiation dose for administration of a radiopharmaceutical to a patient for treatment of a disease may be established by basing the calculation of the appropriate therapeutic dose on factors such as the desired total body dose, the maximum tolerated dose, the typical clearance profile of the radiopharmaceutical, the patient's mass or maximum effective mass, and the patient-specific residence time of the radiopharmaceutical or an analog in the whole body of the patient. The use of the method allows for treatment of a patient with an appropriate dose which is maximally effective against the disease yet minimally toxic. The determination of a patient-specific therapeutic dose may be assisted by the use of a software program set to the particular parameters of the radiopharmaceutical.
    Type: Application
    Filed: August 10, 2005
    Publication date: December 29, 2005
    Applicants: SmithKline Beecham Corporation, The Regents of the University of Michigan
    Inventors: Stewart Kroll, Jeffry Siegal, Richard Wahl, Kenneth Zasadny