Patents by Inventor Jeffry J. Leary

Jeffry J. Leary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide hybridization probes
    Patent number: 4840892
    Abstract: Polynucleotide hybridization probes are labeled in non-probe regions but not in probe regions by selectively protecting probe regions prior to modification of the polynucleotide.
    Type: Grant
    Filed: April 15, 1985
    Date of Patent: June 20, 1989
    Assignee: Smithkline Beckman Corporation
    Inventors: Craig W. Adams, Jeffry J. Leary, Martin Rosenberg
  • Visualization polymers and their application to diagnostic medicine
    Patent number: 4687732
    Abstract: A method for detecting a minute quantity of an inorganic or organic target molecule by combining it with a composition of a detecting agent for the target molecule which carries, by direct or indirect means, a visualization polymer. The visualization polymer is composed of multiple units of a visualization monomer which are covalently linked together directly or indirectly covalently linked together by coupling agents which bond to chemical groups of the monomer. The monomer may be an enzyme, a tagged polypeptide, a tagged polyol, a tagged polyolefin or a tagged carbohydrate. The detecting agent may be an antibody, an enzyme, a lectin, strand of a DNA receptor protein, avidin, streptavidin and the like. The visualization polymer produces a high degree of amplification for the detection of the target molecule.
    Type: Grant
    Filed: June 10, 1983
    Date of Patent: August 18, 1987
    Assignee: Yale University
    Inventors: David C. Ward, Jeffry J. Leary, David J. Brigati