Abstract: Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted.

Abstract: A medical device for stone management comprises a catheter comprising a proximal end, a distal end, and a first lumen and a second lumen disposed therethrough. A handle assembly is interconnected with the proximal end of the catheter, the handle assembly comprising a body defining an interior cavity, a first section and a second section. An interior passageway is disposed within the interior cavity and in fluid communication with the first lumen of the catheter. A valve assembly interconnected with the interior passageway. An actuator assembly is engaged with the valve assembly, the actuator having a first position and a second position. A vacuum port is in communication with the interior passageway and positioned on the second section of the handle. The second section of the handle forms an angle with respect to the first section of the handle.

Abstract: Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a passageway. The passageway has a first inner diameter, a second inner diameter, and a transition chamber. An expandable intraluminal medical device can be loaded into a delivery catheter using the loading apparatus by placing the device into the passageway and pushing the device along an axial path.

Abstract: The present embodiments provide strain relief members for a medical device delivery system, methods of use thereof, and methods of manufacturing. In one embodiment a strain relief member may include a support having a first end with a first outer diameter, a second end having a second outer diameter, an inner surface facing a support lumen that extends axially through the support along a longitudinal axis, and an outer surface opposite to the inner surface. An embodiment may also include an overlay coupled to a portion of the outer surface of the support, where the overlay comprises a first material and the support comprises a second material, and the first material is more flexible than the second material. A liner may be disposed in a portion of the support lumen and a first connector disposed over a portion of the support.

Abstract: Example implantable tissue anchors, kits that include an implantable tissue anchor, and associated methods are described. An example implantable tissue anchor is moveable between a first, expanded configuration and a second, compressed configuration. The implantable tissue anchor has a first end, a second end, and a main body. The main body defines a first arm, a second arm, a first plurality of recesses on the first arm, a first plurality of barbs on the first arm, a second plurality of recess on the second arm, and a second plurality of barbs on the second arm. The first arm and the second arm define a first closed loop and a first passageway that extends through the main body when the implantable tissue anchor is in the first, expanded configuration.

Abstract: A medical device for stone management comprises a catheter comprising a proximal end, a distal end, and a first lumen and a second lumen disposed therethrough. A handle assembly is interconnected with the proximal end of the catheter, the handle assembly comprising a body defining an interior cavity, a first section and a second section. An interior passageway is disposed within the interior cavity and in fluid communication with the first lumen of the catheter. A valve assembly interconnected with the interior passageway. An actuator assembly is engaged with the valve assembly, the actuator having a first position and a second position. A vacuum port is in communication with the interior passageway and positioned on the second section of the handle. The second section of the handle forms an angle with respect to the first section of the handle.

Abstract: A control for an endoscope includes a housing defining an interior volume. A lever external to the housing extends through the housing into the interior volume. A gear system positioned in the interior volume is operatively coupled to the lever. The gear system includes a first quadrant and a second quadrant each configured to pivot about a corresponding axis to deflect a flexible distal tip portion of the endoscope in a corresponding direction.

Abstract: A device for use with a uterine tamponade apparatus, such as the Bakri® postpartum hemorrhage balloon, is disclosed. The device comprises an anchor for deployment within the vagina to securely retain the balloon in its proper position within the uterine cavity, allowing the balloon to function as intended for the control and management of postpartum hemorrhage and uterine bleeding. Methods of use of the vaginal anchor are also disclosed.

Abstract: The present embodiments provide strain relief members for a medical device delivery system, methods of use thereof, and methods of manufacturing. In one embodiment a strain relief member may include a support having a first end with a first outer diameter, a second end having a second outer diameter, an inner surface facing a support lumen that extends axially through the support along a longitudinal axis, and an outer surface opposite to the inner surface. An embodiment may also include an overlay coupled to a portion of the outer surface of the support, where the overlay comprises a first material and the support comprises a second material, and the first material is more flexible than the second material. A liner may be disposed in a portion of the support lumen and a first connector disposed over a portion of the support.

Abstract: The present embodiments provide strain relief members for a medical device delivery system, methods of use, and methods of manufacturing. In one embodiment, a medical device delivery system may include a body member with a first end having a first outer diameter, a second end having a second outer diameter, an inner surface facing a lumen that extends axially through the body member along a longitudinal axis, and an outer surface opposite to the inner surface. The embodiment also includes a threaded first connector at the first end of the body member. The outer surface of the body member may include a plurality of depressions. The body member may include a first material. The first connector may include a second material. The first material is more flexible than the second material. A portion of the outer surface of the body member may cover a portion of the first connector.

Abstract: A device for use with a uterine tamponade balloon catheter apparatus, such as the Bakri postpartum hemorrhage balloon, is disclosed. The device comprises a stylet comprising a hub at its proximal end. The device is configured to be removably coupled to the tamponade balloon catheter apparatus to aid in the insertion and positioning of the tamponade balloon catheter within the uterine cavity, allowing the balloon to function as intended for the control and management of postpartum hemorrhage and uterine bleeding. Methods of use of the device are also disclosed.

Abstract: Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted.

Abstract: Disclosed is a multi-lumen mixing device that includes a first and second lumen constructed and arranged to separately pass a first and second reagent to a mixing chamber in the device, where the mixing chamber includes a mixing feature that mixes the first and second reagents. The disclosed multi-lumen mixing device may also include a port in fluid communication with the reaction mixing to permit the product of the combined reagents to be injected into a patent.

Abstract: Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted.

Abstract: A control for an endoscope includes a housing defining an interior volume. A lever external to the housing extends through the housing into the interior volume. A gear system positioned in the interior volume is operatively coupled to the lever. The gear system includes a first quadrant and a second quadrant each configured to pivot about a corresponding axis to deflect a flexible distal tip portion of the endoscope in a corresponding direction.

Abstract: One aspect of the invention provides an injection catheter system including an elongated sheath having a sheath lumen, extending from a distal end to a proximal end, and a catheter. In one embodiment the catheter includes an elongated member having a lumen and an expandable frame including a plurality of struts extending distally from the distal end of the elongated member and attaching to a tip at their distal ends. A graft material attaches to and extends between a proximal portion of the plurality of struts and to the elongated member, forming a collapsible funnel. Another aspect of the invention provides a method of using such a system for visualizing a target region within a vessel or organ of a subject.

Abstract: A device for use with a uterine tamponade apparatus, such as the Bakri® postpartum hemorrhage balloon, is disclosed. The device comprises an anchor for deployment within the vagina to securely retain the balloon in its proper position within the uterine cavity, allowing the balloon to function as intended for the control and management of postpartum hemorrhage and uterine bleeding. Methods of use of the vaginal anchor are also disclosed.

Abstract: A device for obtaining selective rigidity with respect to a patient is provided. The device includes a scaffold that is arranged to be flexible when in a first relaxed configuration, wherein the scaffold is configured to become substantially more rigid when a suction force is applied thereto. The scaffold comprises first and second opposing outer flexible layers that are sealed together to form a plurality of elongate pockets therein, and an expanded structure disposed within the plurality of elongate pockets and in communication with a vacuum port that receives the suction force.

Abstract: A device for use with a uterine tamponade balloon catheter apparatus, such as the Bakri postpartum hemorrhage balloon, is disclosed. The device comprises a stylet comprising a hub at its proximal end. The device is configured to be removably coupled to the tamponade balloon catheter apparatus to aid in the insertion and positioning of the tamponade balloon catheter within the uterine cavity, allowing the balloon to function as intended for the control and management of postpartum hemorrhage and uterine bleeding. Methods of use of the device are also disclosed.

Abstract: A multiple catheter system including an imaging scope having an elongated body having a first length and a first outer diameter. The elongated body including a first passage extending along the first length. A flexible distal tip portion is coupled to the elongated body. The flexible distal tip portion includes an imaging sensor and a light source. A proximal connector is coupled to the elongated body opposite the flexible distal tip portion. The proximal connector has a second outer diameter not greater than the first outer diameter. A first catheter includes a flexible distal tip portion and a first lateral extension disposed at the flexible distal tip portion. The first lateral extension includes a second passage having an inner diameter greater than the first outer diameter and the second outer diameter, wherein the imaging scope is movably positionable within the second passage.