Patents by Inventor Jen-Chih Hsieh

Jen-Chih Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230049346
    Abstract: A ground fault detection apparatus is used to detect a ground fault of a three-phase UPS apparatus. The UPS apparatus includes a first filter circuit, an AC/DC conversion circuit, a DC bus, a DC/AC conversion circuit, and a second filter circuit coupled in sequence. The ground fault detection apparatus includes a detection circuit having a first detection end and a second detection end. The first detection end is coupled to the first filter circuit and the second filter circuit, and the second detection end is coupled to an equipment grounding point. The equipment grounding point is coupled to a neutral point of a three-phase power source, and the three-phase power source is coupled to the first filter circuit. The detection circuit indicates whether the UPS apparatus has a ground fault and a location where the ground fault occurs according to a detection voltage between the first detection end and the second detection end.
    Type: Application
    Filed: November 17, 2021
    Publication date: February 16, 2023
    Inventors: Hung-Chieh LIN, Jen-Chuan LIAO, Yi-Ping HSIEH, Hsin-Chih CHEN
  • Publication number: 20220401956
    Abstract: A drug screening platform simulating hyperthermic intraperitoneal chemotherapy including a dielectrophoresis system, a microfluidic chip and a heating system is disclosed. The dielectrophoresis system is used to provide a dielectrophoresis force. The microfluidic chip includes a cell culture array and observation module and a drug mixing module. The cell culture array and observation module are used to arrange the cells into a three-dimensional structure through the dielectrophoresis force to construct a three-dimensional tumor microenvironment. The drug mixing module is coupled to the cell culture array and observation module and used to automatically split and mix the inputted drugs and output the drug combinations into the cell culture array and observation module.
    Type: Application
    Filed: August 5, 2021
    Publication date: December 22, 2022
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Te-Yu CHAO, Yu-Ching TUNG, Mao-Chih HSIEH, Yu-Ting TAI, Bing-Ying HO, Wei-Chia CHANG, Sung-Yang WEI, Chang-Hung HSIEH, Chung-Cheng CHOU, Jen-Tsan CHI, Long HSU, Hwan-You CHANG, Huang-Ming Philip CHEN, Cheng-Hsien LIU
  • Patent number: 11033567
    Abstract: This invention is directed to compositions for promoting wound healing and regeneration and methods of use thereof. In one aspect, methods for promoting wound healing in a subject are provided, the methods comprising: administering a therapeutically effective amount of a DNA methyl transferase inhibitors (DNMT) to the subject. In another aspect, methods for reducing scarring during healing of a skin wound are provided, the methods comprising: administering a therapeutically effective amount of a DNMT inhibitor.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: June 15, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: George Cotsarelis, Jen-Chih Hsieh, Ying Zheng
  • Publication number: 20200078351
    Abstract: DP-2 antagonists reversed PGD2-mediated human hair growth inhibition in a dose-dependent manner in vitro by reducing PGD2-triggered apoptosis and maintaining proliferation of keratinocytes. Hair follicles from approximately half of the alopecia patients exhibited little susceptibility to PGD2's effect in vitro. SNPs in the human DP-2 gene were identified that are associated with hair growth inhibition by PGD2. These findings underscore the role of DP-2 in regulating hair growth and indicate that DP-2 can be an effective approach in preventing and/or treating androgenetic alopecia in patients sensitive to PGD2. Furthermore, the SNPs identified here can be used to identify patients who will benefit from treatment.
    Type: Application
    Filed: July 28, 2016
    Publication date: March 12, 2020
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: George Cotsarelis, Ying Zheng, Jen-Chih Hsieh
  • Publication number: 20170209475
    Abstract: This invention is directed to compositions for promoting wound healing and regeneration and methods of use thereof. In one aspect, methods for promoting wound healing in a subject are provided, the methods comprising: administering a therapeutically effective amount of a DNA methyl transferase inhibitors (DNMT) to the subject. In another aspect, methods for reducing scarring during healing of a skin wound are provided, the methods comprising: administering a therapeutically effective amount of a DNMT inhibitor.
    Type: Application
    Filed: July 21, 2015
    Publication date: July 27, 2017
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANNIA
    Inventors: George COTSARELIS, Jen-Chih HSIEH, Ying ZHENG
  • Publication number: 20070269808
    Abstract: Wnt receptor compositions and methods of use are disclosed. In particular, methods using Wnt receptors, such as Dfz2, in screens for compounds which modulate the binding of a Wnt polypeptide to a Wnt receptor.
    Type: Application
    Filed: March 6, 2006
    Publication date: November 22, 2007
    Inventors: Purnima Bhanot, Marcel Brink, Cindy Samos, Yanshu Wang, Jen-Chih Hsieh, Deborah Andrew, Jeremy Nathans, Roeland Nusse
  • Publication number: 20030040051
    Abstract: Wnt receptor compositions and methods of use are disclosed. In particular, methods using Wnt receptors, such as Dfz2, in screens for compounds which modulate the binding of a Wnt polypeptide to a Wnt receptor.
    Type: Application
    Filed: May 21, 2002
    Publication date: February 27, 2003
    Inventors: Purnima Bhanot, Marcel Brink, Cindy H. Samos, Yanshu Wang, Jen-Chih Hsieh, Deborah Andrew, Jeremy Nathans, Roeland Nusse