Patents by Inventor Jenai Quan

Jenai Quan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid sequence enrichment by defined nucleic acid-directed endonuclease digestion
    Patent number: 11987837
    Abstract: A method of sample analysis is described comprising providing a sample comprising a plurality of endblocked polynucleotides, digesting the sample with one or more defined nucleic acid-directed endonuclease that targets a sequence of interest to produce a digested sample of polynucleotide fragments, wherein one or more of the fragments in the digested sample comprises: a sequence of interest and at least one ligatable end that has been generated by endonuclease cleavage; (c) enriching for fragments that contain the sequence of interest, wherein the one or more sequences of interest are enriched greater than 55 times, or greater than 750 times, their relative abundance in the sample; and (d) analyzing the enriched sample.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: May 21, 2024
    Assignee: CZ Biohub SF, LLC
    Inventors: Emily D. Crawford, Jenai Quan
  • NUCLEIC ACID SEQUENCE ENRICHMENT BY DEFINED NUCLEIC ACID-DIRECTED ENDONUCLEASE DIGESTION
    Publication number: 20210198719
    Abstract: A method of sample analysis is described comprising providing a sample comprising a plurality of endblocked polynucleotides, digesting the sample with one or more defined nucleic acid-directed endonuclease that targets a sequence of interest to produce a digested sample of polynucleotide fragments, wherein one or more of the fragments in the digested sample comprises: a sequence of interest and at least one ligatable end that has been generated by endonuclease cleavage; (c) enriching for fragments that contain the sequence of interest, wherein the one or more sequences of interest are enriched greater than 55 times, or greater than 750 times, their relative abundance in the sample; and (d) analyzing the enriched sample.
    Type: Application
    Filed: August 6, 2019
    Publication date: July 1, 2021
    Inventors: Emily D. Crawford, Jenai Quan