Abstract: Described herein are light-activatable, sustained-exposure compositions for the treatment and monitoring of diseases along with methods of making and using the same, wherein the compositions comprise a solvent, a cellulosic polymer, a photosensitizer, and optionally additional therapeutic agents. In some embodiments, an additional therapeutic agent is included. The compositions can be administered to a target in need, such as a tumor or lesion, and activated with a light source to induce necrosis or apoptosis and to track the distribution of the composition at the target site. Beneficially the compositions provide synergistic ablation and photodynamic efficacy.

Abstract: A colposcope includes an inserter including an elongated body defining an interior space and an image capture device configured to be selectively and slidably positioned within the interior space of the elongated body. The elongated body has a distal end portion and a proximal end portion. The distal end portion is substantially funnel shaped and has a distal end that includes first and second portions. The first portion includes a base at a first edge of the distal end, and the second portion includes a lip at a second edge of the distal end that is diametrically opposed from the first edge. The lip is positioned further from the proximal end portion than the base.

Abstract: A colposcope includes an inserter including an elongated body defining an interior space and an image capture device configured to be selectively and slidably positioned within the interior space of the elongated body. The elongated body has a distal end portion and a proximal end portion. The distal end portion is substantially funnel shaped and has a distal end that includes first and second portions. The first portion includes a base at a first edge of the distal end, and the second portion includes a lip at a second edge of the distal end that is diametrically opposed from the first edge. The lip is positioned further from the proximal end portion than the base.

Abstract: Disclosed herein are colposcopes, mammoscopes, and speculum-free imaging methods (inserters) having curved ends and flat ends and associated methods. According to an aspect, an inserter includes an elongate body defining an interior space and having a distal end, a proximate end, and an axis extending between the distal end and the proximate end. The distal end is substantially funnel shaped and defines a wide portion and a narrow portion. The narrow portion is closer to the proximate end than the wide portion. An edge of a first portion of the wide portion extends further from the proximate end than an edge of a second portion of the wide portion.