Abstract: Systems and methods for an item placement configuration optimization are provided. A system and method can include receiving a first selection including two or more first items corresponding to a first level in an item placement configuration. A first score is determined for the first selection by applying an algorithm to data corresponding to the first items. A second selection including two or more second items and corresponding to a second level in the item placement configuration is received. A second score for the second selection is determined by applying an algorithm to the first score and data corresponding to the second items.