Patents by Inventor Jennifer A. Chaplin

Jennifer A. Chaplin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrilases, nucleic acids encoding them and methods for making and using them
    Patent number: 9217164
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: December 22, 2015
    Assignee: BASF Enzymes LLC
    Inventors: Jennifer A. Chaplin, Ellen Chi, Grace DeSantis, Mark Madden, Darcy Madden, Aileen Milan, Dan E. Robertson, Jay M. Short, David P. Weiner
  • Methods for Making Simvastatin and Intermediates
    Publication number: 20110059493
    Abstract: The invention provides synthetic chemical and chemoenzymatic methods of producing simvastatin and various intermediates. In one aspect, enzymes such as hydrolases, e.g., esterases, are used in the methods of the invention.
    Type: Application
    Filed: April 19, 2010
    Publication date: March 10, 2011
    Inventors: Brian Morgan, Mark Burk, Michael Levin, Zuolin Zhu, Jennifer Chaplin, Karen Kustedjo, Zilin Huang, William Greenberg
  • Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them
    Publication number: 20100273659
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: February 29, 2008
    Publication date: October 28, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Grace DeSantis, Jennifer Chaplin, Ellen Chi, Aileen Milan, Jay Short, David Weiner, Mark Madden, Darcy Madden, Dan Robertson
  • Methods for making simvastatin and intermediates
    Patent number: 7700329
    Abstract: The invention provides synthetic chemical and chemoenzymatic methods of producing simvastatin and various intermediates. In one aspect, enzymes such as hydrolases, e.g., esterases, are used in the methods of the invention.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: April 20, 2010
    Inventors: Brian Morgan, Mark Burk, Michael Levin, Zuolin Zhu, Jennifer Chaplin, Karen Kustedjo, Zilin Huang, William Greenberg
  • Methods for Making Simvastatin and Intermediates
    Publication number: 20080182303
    Abstract: The invention provides synthetic chemical and chemoenzymatic methods of producing simvastatin and various intermediates. In one aspect, enzymes such as hydrolases, e.g., esterases, are used in the methods of the invention.
    Type: Application
    Filed: October 20, 2004
    Publication date: July 31, 2008
    Inventors: Brian Morgan, Mark Burk, Michael Levin, Zuolin Zhu, Jennifer Chaplin, Karen Kustedjo, Zillin Huang, William Greenberg