Patents by Inventor Jennifer Anne Cain

Jennifer Anne Cain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of dermal fibrosis
    Patent number: 10064937
    Abstract: The present invention relates to RSPO and LGR antagonists, and methods of using the RSPO and LGR antagonists for treating or preventing fibrotic diseases.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: September 4, 2018
    Assignee: OncoMed Pharmaceuticals, Inc.
    Inventor: Jennifer Anne Cain
  • COMBINATION THERAPY FOR TREATMENT OF DISEASE
    Publication number: 20180244783
    Abstract: The present invention provides methods comprising combination therapy for modulating immune responses, for inhibiting tumor growth, and/or for treating cancer. In particular, the present invention provides Wnt pathway inhibitors in combination with immunotherapeutic agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: August 31, 2016
    Publication date: August 30, 2018
    Inventors: Timothy Charles HOEY, Christopher Lamond MURRIEL, Jennifer Anne CAIN
  • Treatment of Fibrotic Diseases
    Publication number: 20160166684
    Abstract: The present invention relates to RSPO and LGR antagonists, and methods of using the RSPO and LGR antagonists for treating or preventing fibrotic diseases.
    Type: Application
    Filed: September 15, 2015
    Publication date: June 16, 2016
    Inventor: Jennifer Anne CAIN
  • Human Notch Receptor Mutations and Their Use
    Publication number: 20150316552
    Abstract: The present invention provides the identification and characterization of NOTCH mutations associated with enhanced receptor signaling. The present invention provides methods and kits for using the same. The present invention further provides methods of treating cancer in a patient having a solid tumor, wherein the solid tumor cells comprise an elevated level of NOTCH ICD.
    Type: Application
    Filed: November 14, 2012
    Publication date: November 5, 2015
    Inventors: Jennifer Anne Cain, Min Wang, Ann M. Kapoun, Timothy C. Hoey
  • Methods of Treating Hematological Malignancies with Notch1 Antibodies
    Publication number: 20150232570
    Abstract: NOTCH1-binding antibodies and methods of using the antibodies for treating hematologic cancers are disclosed. Methods of using antibodies that bind to a non-ligand binding membrane proximal region of the extracellular domain of human NOTCH1 and methods of treating chronic lymphocytic leukemia (CLL), hairy cell leukemia, chronic myelogenous leukemia (CML), nonHodgkin lymphoma, diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL), or cutaneous T-cell lymphoma (CTCL) in a subject, comprising administering a therapeutically effective amount of a NOTCH1-binding antibody to the subject are also disclosed. Methods of identifying subjects suitable for such treatment methods are further disclosed.
    Type: Application
    Filed: September 20, 2013
    Publication date: August 20, 2015
    Applicant: ONCOMED PHARMACEUTICALS, INC.
    Inventors: Timothy C. Hoey, Ann M. Kapoun, Min Wang, Tzu-Ling Tang Lin, Jennifer Anne Cain, Jakob Dupont