Patents by Inventor Jennifer BORDEAUX

Jennifer BORDEAUX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11747319
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: September 5, 2023
    Assignee: Novartis AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Patent number: 11726092
    Abstract: The invention relates, in part, to methods of scoring a sample containing tumor tissue from a cancer patient. The score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: August 15, 2023
    Assignee: Novartis AG
    Inventors: Naveen Dakappagari, Thai Tran, Brian Little, Ju Young Kim, Jennifer Bordeaux
  • Publication number: 20230017087
    Abstract: The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Application
    Filed: September 20, 2022
    Publication date: January 19, 2023
    Applicant: Novartis AG
    Inventors: Naveen DAKAPPAGARI, Jennifer BORDEAUX, Thai TRAN, Ju Young KIM
  • Patent number: 11480570
    Abstract: The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: October 25, 2022
    Assignee: NOVARTIS AG
    Inventors: Naveen Dakappagari, Jennifer Bordeaux, Thai Tran, Ju Young Kim
  • Patent number: 11430111
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy. The invention also relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: August 30, 2022
    Assignee: Novartis AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Publication number: 20220170905
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Applicant: Novartis AG
    Inventors: Brian Little, Jennifer BORDEAUX
  • Patent number: 11249066
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: February 15, 2022
    Assignee: Novartis AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Publication number: 20200300834
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 24, 2020
    Applicant: Novartis AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Publication number: 20200292550
    Abstract: The invention relates, in part, to methods of scoring a sample containing tumor tissue from a cancer patient. The score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Application
    Filed: June 2, 2020
    Publication date: September 17, 2020
    Applicant: Novartis AG
    Inventors: Naveen DAKAPPAGARI, Thai TRAN, Brian LITTLE, Ju Young KIM, Jennifer BORDEAUX
  • Publication number: 20200286230
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy. The invention also relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Application
    Filed: March 18, 2020
    Publication date: September 10, 2020
    Applicant: Novartis AG
    Inventors: Brian LITTLE, Jennifer BORDEAUX
  • Patent number: 10712331
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: July 14, 2020
    Assignee: Novartis AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Patent number: 10705088
    Abstract: The invention relates, in part, to methods of scoring a sample containing tumor tissue from a cancer patient. The score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: July 7, 2020
    Assignee: NOVARTIS AG
    Inventors: Naveen Dakappagari, Thai Tran, Brian Little, Ju Young Kim, Jennifer Bordeaux
  • Patent number: 10621721
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy. The invention also relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: April 14, 2020
    Assignee: NOVARTIS AG
    Inventors: Brian Little, Jennifer Bordeaux
  • Publication number: 20200049714
    Abstract: The invention relates, in part, to methods of predicting a likelihood that a cancer patient will respond positively to immunotherapy. The methods include scoring a sample containing tumor tissue from a cancer patient, wherein the score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker, and deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from the cancer patient.
    Type: Application
    Filed: February 5, 2018
    Publication date: February 13, 2020
    Applicant: Novartis AG
    Inventors: Jennifer BORDEAUX, Naveen DAKAPPAGARI, Ju Young KIM
  • Publication number: 20190293648
    Abstract: The invention relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Application
    Filed: October 21, 2016
    Publication date: September 26, 2019
    Applicant: Novartis AG
    Inventors: Naveen DAKAPPAGARI, Jennifer BORDEAUX, Thai TRAN, Ju Young KIM
  • Publication number: 20190056404
    Abstract: The invention relates, in part, to methods of scoring a sample containing tumor tissue from a cancer patient. The score is representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Application
    Filed: October 21, 2016
    Publication date: February 21, 2019
    Applicant: Novartis AG
    Inventors: Naveen DAKAPPAGARI, Thai TRAN, Brian LITTLE, Ju KIM, Jennifer BORDEAUX
  • Publication number: 20180330498
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy. The invention also relates, in part, to methods of deriving a value for % biomarker positivity (PBP) for all cells or optionally, one or more subsets thereof, present in a field of view of a tissue sample from a cancer patient. The values for PBP can be indicative of a patient's response to immunotherapy.
    Type: Application
    Filed: October 21, 2016
    Publication date: November 15, 2018
    Applicant: Novartis AG
    Inventors: Brian LITTLE, Jennifer BORDEAUX
  • Publication number: 20180306768
    Abstract: The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.
    Type: Application
    Filed: October 21, 2016
    Publication date: October 25, 2018
    Applicant: Novartis AG
    Inventors: Brian LITTLE, Jennifer BORDEAUX