Abstract: There are disclosed novel anti-ROR1 macrocyclic peptides and their conjugates with general structure of formula (I), which can be used as ROR1 inhibitors.

Abstract: Examples are disclosed for automatic downstream to upstream mode switching at a universal serial bus (USB) physical (PHY) layer including activating a switching structure to switch a USB port operating in a downstream mode to an upstream mode based on an attempted attachment by another USB port also operating in a downstream mode. The examples may also include facilitating attachment of the switched USB port now operating in the upstream mode to the other USB port operating in the downstream mode.

Abstract: A signal transmission system includes a controller interface, a protocol engine to convert data based on at least one protocol, and a common protocol interface coupled between the controller interface and the protocol engine. The controller interface includes or is coupled to a common dispatcher, and the data is to be transmitted between the controller interface and protocol engine through the common protocol interface and common dispatcher. The same protocol engine may convert data into different protocols, with all of the converted data be transmitted to or received from the controller interface through the common dispatcher and common protocol interface.

Abstract: Examples are disclosed for automatic downstream to upstream mode switching at a universal serial bus (USB) physical (PHY) layer including activating a switching structure to switch a USB port operating in a downstream mode to an upstream mode based on an attempted attachment by another USB port also operating in a downstream mode. The examples may also include facilitating attachment of the switched USB port now operating in the upstream mode to the other USB port operating in the downstream mode.

Abstract: Systems and methods of operating root hub host controllers provide for determining, at a protocol engine having a dedicated port, a speed of a device in response to a coupling of the device to the dedicated port. Data transfer can occur at a second speed between software interface logic of the host controller and the protocol engine, and at the first speed between the protocol engine and the device via the dedicated port, wherein the second speed is greater than the first speed. In addition, data may be transferred in unicast transactions in which no split tokens are exchanged.

Abstract: A signal transmission system includes a controller interface, a protocol engine to convert data based on at least one protocol, and a common protocol interface coupled between the controller interface and the protocol engine. The controller interface includes or is coupled to a common dispatcher, and the data is to be transmitted between the controller interface and protocol engine through the common protocol interface and common dispatcher. The same protocol engine may convert data into different protocols, with all of the converted data be transmitted to or received from the controller interface through the common dispatcher and common protocol interface.

Abstract: Systems and methods of operating root hub host controllers provide for determining, at a protocol engine having a dedicated port, a speed of a device in response to a coupling of the device to the dedicated port. Data transfer can occur at a second speed between software interface logic of the host controller and the protocol engine, and at the first speed between the protocol engine and the device via the dedicated port, wherein the second speed is greater than the first speed. In addition, data may be transferred in unicast transactions in which no split tokens are exchanged.

Abstract: A system to monitor performance of a computing device includes a first bridge to interface with a first set of devices, and a second bridge to interface with a second set of devices. Configuration registers store configuration data associated with the second set of devices, and are accessible through the second bridge. A hub interface allows data to transfer downstream from the first bridge to the second bridge, and allows data to transfer upstream from the second bridge to the first bridge. A controller, external to the first and second bridges, accesses the configuration registers via the second bridge. A logic device allows the second bridge to send data to, and receive data from, the controller.

Abstract: A system to monitor performance of a computing device includes a first bridge to interface with a first set of devices, and a second bridge to interface with a second set of devices. Configuration registers store configuration data associated with the second set of devices, and are accessible through the second bridge. A hub interface allows data to transfer downstream from the first bridge to the second bridge, and allows data to transfer upstream from the second bridge to the first bridge. A controller, external to the first and second bridges, accesses the configuration registers via the second bridge. A logic device allows the second bridge to send data to, and receive data from, the controller.

Abstract: Embodiments of the present invention provide a system event log for a computer system. The system event log may comprise a RAM coupled to a system bus. The system event log may be configured to record information in the RAM corresponding to bus transactions on the system bus. The information may be used to de-bug system problems.

Abstract: The present invention relates to a system and method to implement a cost-effective remote system management mechanism using a serial communication controller and interrupts. The system includes a requesting device operatively coupled to a network to send a status query through a serial port in the requesting device. The system further includes a responding device operatively coupled to the network to receive the status query from the requesting device. The status query inquires about operational status of the responding device. The responding device receives the status query through a serial port in the responding device, processes the status query, and reports the operational status through the serial port in the responding device to the requesting device in response to the status query sent by the requesting device.

Abstract: According to one embodiment of the invention, a first signal line is provided for a serial interface unit (SIU) of an I/O controller to report interrupt requests to an interrupt controller. In one embodiment, a transition of the first signal line from a first level (e.g., low level or logic 0) to a second level (e.g., high level or logic 1) indicates a pending interrupt to the interrupt controller. A pull up resistor is provided to pull the first signal line to the second level when the first signal line is not driven by the SIU. In response to detecting an interrupt request initiated by an I/O device, a transition from the first level to the second level is generated on the first signal line for a predetermined duration to report the pending interrupt request to the interrupt controller.

Abstract: The present invention relates to a system and method to implement a cost-effective remote system management mechanism using a serial communication controller and interrupts. The system includes a requesting device operatively coupled to a network to send a status query through a serial port in the requesting device. The system further includes a responding device operatively coupled to the network to receive the status query from the requesting device. The status query inquires about operational status of the responding device. The responding device receives the status query through a serial port in the responding device, processes the status query, and reports the operational status through the serial port in the responding device to the requesting device in response to the status query sent by the requesting device.

Abstract: Embodiments of the present invention provide a system event log for a computer system. The system event log may comprise a RAM coupled to a system bus. The system event log may be configured to record information in the RAM corresponding to bus transactions on the system bus. The information may be used to de-bug system problems.

Abstract: According to one embodiment of the invention, a first signal line is provided for a serial interface unit (SIU) of an I/O controller to report interrupt requests to an interrupt controller. In one embodiment, a transition of the first signal line from a first level (e.g., low level or logic 0) to a second level (e.g., high level or logic 1) indicates a pending interrupt to the interrupt controller. A pull up resistor is provided to pull the first signal line to the second level when the first signal line is not driven by the SIU. In response to detecting an interrupt request initiated by an I/O device, a transition from the first level to the second level is generated on the first signal line for a predetermined duration to report the pending interrupt request to the interrupt controller.

Abstract: A system to monitor performance of a computing device includes a first bridge to interface with a first set of devices, and a second bridge to interface with a second set of devices. Configuration registers store configuration data associated with the second set of devices, and are accessible through the second bridge. A hub interface allows data to transfer downstream from the first bridge to the second bridge, and allows data to transfer upstream from the second bridge to the first bridge. A controller, external to the first and second bridges, accesses the configuration registers via the second bridge. A logic device allows the second bridge to send data to, and receive data from, the controller.

Abstract: The present invention pertains to a bead-weaving system comprising means for spacing apart a multiplicity of warp threads, each of said beads being pierced by a hole through their diameter and intended to be threaded on a weft thread by means of a needle and to be positioned between each warp thread