Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for machine learning for home understanding and notification. In one aspect, a method includes obtaining reference videos from a camera within a premises of a home, determining, from the reference videos, timing of actions in a routine that a particular person performs before leaving the home, determining from a sample video from the camera within the home that the particular person appears to be out of sync in performing a particular action based on the timing of actions in the routine determined from the reference videos, and in response, providing a notification to the particular person.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for machine learning for home understanding and notification. In one aspect, a method includes obtaining reference videos from a camera within a premises of a home, determining, from the reference videos, timing of actions in a routine that a particular person performs before leaving the home, determining from a sample video from the camera within the home that the particular person appears to be out of sync in performing a particular action based on the timing of actions in the routine determined from the reference videos, and in response, providing a notification to the particular person.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for machine learning for home understanding and notification. In one aspect, a method includes obtaining reference videos from a camera within a premises of a home, determining, from the reference videos, timing of actions in a routine that a particular person performs before leaving the home, determining from a sample video from the camera within the home that the particular person appears to be out of sync in performing a particular action based on the timing of actions in the routine determined from the reference videos, and in response, providing a notification to the particular person.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for machine learning for home understanding and notification. In one aspect, a method includes obtaining reference videos from a camera within a premises of a home, determining, from the reference videos, timing of actions in a routine that a particular person performs before leaving the home, determining from a sample video from the camera within the home that the particular person appears to be out of sync in performing a particular action based on the timing of actions in the routine determined from the reference videos, and in response, providing a notification to the particular person.

Abstract: The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

Abstract: The present invention relates to novel pyrimidine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

Abstract: The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.

Abstract: The invention thus provides the compounds of formula (I) and pharmaceutically acceptable salts thereof, in which: R1 and R2 are independently selected from the group consisting of H, C1-6alkyl, C2-6alkenyl, C3-6alkynyl, C3-10cycloalkylC0-6alkyl and C4-12bridged cycloalkyl; R3 is selected from the group consisting of C1-6alkyl, NH2 and R5CONH; R4 is selected from the group consisting of CH2F, CHF2, CF3CH2, CF3CHF and CF3CF2; and R5 is selected from the group consisting of H, C1-6alkyl, C1-6alkoxy, C1-6alkylOC1-6alkyl, phenyl, HO2CC1-6alkyl, C1-6alkylOCOC1-6alkyl, C1-6alkylOCO, H2NC1-6alkyl, C1-6alkylOCONHC1-6alkyl and C1-6alkylCONHC1-6alkyl. Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases.

Abstract: Methods of treating a subject suffering from a condition which is mediated by COX-2.

Abstract: The invention thus provides the compounds of formula (I) and pharmaceutically acceptable salts thereof, in which: R1 and R2 are independently selected from the group consisting of H, C1-6alkyl, C2-6alkenyl, C3-4alkynyl, C3-10cycloalkylC0-6alkyl and C4-12bridged cycloalkyl; R3 is selected from the group consisting of C1-6alkyl, NH2 and R5CONH; R4 is selected from the group consisting of CH2F, CHF2, CF3CH2, CF3CHF and CF3CF2; and R5 is selected from the group consisting of H, C1-6alkyl, C1-6alkoxy, C1-6alkylOC1-6alkyl, phenyl, HO 2cc1-6?alkyl, C1-6alkylOCOC1-6alkyl, C1-4alkylOCO, H2NC1-6alkyl, C1-6alkylOCONHC1-6alkyl and C1-6alkylCONHC1-6alkyl. Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases.