Patents by Inventor Jennifer LAVALLEE

Jennifer LAVALLEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZATION OF FC-CONTAINING POLYPEPTIDES
    Publication number: 20190192628
    Abstract: This disclosure provides polypeptides comprising an antibody Fc region having a deletion of one or more cysteine residues in the hinge region and substitution with a sulfhydryl-containing residue of one or more CH3-interface amino acids. Also, provided are Fc-fusion proteins and antibodies containing said polypeptides, nucleic acids and vectors encoding said polypeptides, along with host cells and methods for making said polypeptides.
    Type: Application
    Filed: March 8, 2019
    Publication date: June 27, 2019
    Applicant: AMGEN INC.
    Inventors: Gunasekaran KANNAN, Jennifer LAVALLEE, Frederick W. JACOBSEN
  • STABILIZATION OF FC-CONTAINING POLYPEPTIDES
    Publication number: 20160193295
    Abstract: This disclosure provides polypeptides comprising an antibody Fc region having a deletion of one or more cysteine residues in the hinge region and substitution with a sulfhydryl-containing residue of one or more CH3-interface amino acids. Also, provided are Fc-fusion proteins and antibodies containing said polypeptides, nucleic acids and vectors encoding said polypeptides, along with host cells and methods for making said polypeptides.
    Type: Application
    Filed: July 30, 2014
    Publication date: July 7, 2016
    Applicant: AMGEN INC.
    Inventors: Gunasekaran KANNAN, Jennifer LAVALLEE, Frederick W. JACOBSEN