Patents by Inventor Jennifer Li-Pook-Than

Jennifer Li-Pook-Than has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-ACYLATED HISTIDINE DIPEPTIDES AS ANTICANCER AGENTS
    Publication number: 20240124520
    Abstract: N-Acylated histidine dipeptides of formula are disclosed. The compounds are useful for treating breast cancer.
    Type: Application
    Filed: October 10, 2020
    Publication date: April 18, 2024
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Michael BRUNO, Jijuan GU URBAN, Jennifer LI-POOK-THAN, Teri SLIFER, Michael SNYDER
  • Method and system for phasing individual genomes in the context of clinical interpretation
    Patent number: 9928338
    Abstract: The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: March 27, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hua Tang, Michael Snyder, Jennifer Li-Pook Than, Konrad J. Karczewski, Nicholas Johnson, Wing H. Wong
  • Method And System For Phasing Individual Genomes In The Context Of Clinical Interpretation
    Publication number: 20130085728
    Abstract: The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants.
    Type: Application
    Filed: June 1, 2012
    Publication date: April 4, 2013
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hua Tang, Michael Snyder, Jennifer Li-Pook-Than, Konrad J. Karczewski, Nicholas Johnson, Wing H. Wong