Patents by Inventor Jennifer M. Caron

Jennifer M. Caron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR AN ANTIBODY DRUG CONJUGATE DIRECTED TO A NON-CELL SURFACE THERAPEUTIC TARGET
    Publication number: 20240358850
    Abstract: The present invention provides compositions and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases with antibodies an antigen binding fragments thereof which bind collagen and antibody drug conjugates (ADC). In some embodiments, in the methods provided herein the ADCs target non-cell surface targets associated with tumors.
    Type: Application
    Filed: April 12, 2024
    Publication date: October 31, 2024
    Inventors: Peter C. Brooks, Jennifer M. Caron
  • METHODS AND COMPOSITION FOR THE SELECTIVE ENHANCEMENT OF ADOPTIVE CELL THERAPY
    Publication number: 20240327506
    Abstract: The present invention provides compositions and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases by enhancing adoptive cell therapy. In some embodiments, the methods provided herein increase T-cell infiltration into a tumor.
    Type: Application
    Filed: March 28, 2024
    Publication date: October 3, 2024
    Inventors: Xianghua Han, Jennifer M. Caron, Peter C. Brooks
  • Enhancing the therapeutic activity of an immune checkpoint inhibitor
    Patent number: 11998600
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: June 4, 2024
    Assignee: MaineHealth
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • ENHANCING THE THERAPEUTIC ACTIVITY OF IMMUNE CHECKPOINT INHIBITOR
    Publication number: 20210155696
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Application
    Filed: December 9, 2020
    Publication date: May 27, 2021
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • ENHANCING THE THERAPEUTIC ACTIVITY OF AN IMMUNE CHECKPOINT INHIBITOR
    Publication number: 20210100901
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Application
    Filed: December 3, 2020
    Publication date: April 8, 2021
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • Enhancing the therapeutic activity of immune checkpoint inhibitor
    Patent number: 10906977
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: February 2, 2021
    Assignee: Maine Medical Center Research Institute
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • Enhancing the therapeutic activity of an immune checkpoint inhibitor
    Patent number: 10881732
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: January 5, 2021
    Assignee: Maine Medical Center Research Institute
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • Compositions and methods for treating inflammation and fibrosis
    Patent number: 9890208
    Abstract: The present invention features compositions featuring agents that bind to denatured collagen and methods of using such agents to treat or prevent fibrosis or inflammation in a subject.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: February 13, 2018
    Assignee: Maine Medical Center
    Inventors: Peter C. Brooks, Leif Oxburgh, Jennifer M. Caron
  • ENHANCING THE THERAPEUTIC ACTIVITY OF IMMUNE CHECKPOINT INHIBITOR
    Publication number: 20170240638
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Peter C. Brooks, Jennifer M. Caron
  • ENHANCING THE THERAPEUTIC ACTIVITY OF AN IMMUNE CHECKPOINT INHIBITOR
    Publication number: 20170065716
    Abstract: The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
    Type: Application
    Filed: June 1, 2016
    Publication date: March 9, 2017
    Inventors: Peter C. Brooks, Jennifer M. Caron, Liangru Contois
  • COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND FIBROSIS
    Publication number: 20150010552
    Abstract: The present invention features compositions featuring agents that bind to denatured collagen and methods of using such agents to treat or prevent fibrosis or inflammation in a subject.
    Type: Application
    Filed: September 17, 2014
    Publication date: January 8, 2015
    Inventors: Peter C. Brooks, Leif Oxburgh, Jennifer M. Caron