Patents by Inventor Jennifer M. Harvard

Jennifer M. Harvard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, peptides, and biosensors useful for detecting a broad spectrum of bacteria
    Patent number: 9315851
    Abstract: Described herein are methods of detecting a wound infection and for detecting the presence or absence of bacteria, for example, wound bacteria in a sample, by contacting a sample with a peptide substrate derived from the modification of the reactive site loop (RSL) domain of the ?1-proteinase inhibitor. In the current invention, we have demonstrated that these peptide substrates without the alpha 1 protein can be efficiently used as peptide substrates. The modification or the absence of modification of this peptide substrate by the enzyme produced and/or secreted by the bacteria, can serve as an indicator for the presence or absence of the bacteria in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: April 19, 2016
    Assignee: Woundchek Laboratories (US), Inc.
    Inventors: Shite Sebastian, Gerard J. Colpas, Diane L. Ellis-Busby, Jennifer M. Harvard, Mitchell C. Sanders
  • Methods, Peptides, and Biosensors Useful for Detecting a Broad Spectrum of Bacteria
    Publication number: 20150184220
    Abstract: Described herein are methods of detecting a wound infection and for detecting the presence or absence of bacteria, for example, wound bacteria in a sample, by contacting a sample with a peptide substrate derived from the modification of the reactive site loop (RSL) domain of the ?1-proteinase inhibitor. In the current invention, we have demonstrated that these peptide substrates without the alpha 1 protein can be efficiently used as peptide substrates. The modification or the absence of modification of this peptide substrate by the enzyme produced and/or secreted by the bacteria, can serve as an indicator for the presence or absence of the bacteria in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
    Type: Application
    Filed: December 18, 2014
    Publication date: July 2, 2015
    Inventors: Shite Sebastian, Gerard J. Colpas, Diane L. Ellis-Busby, Jennifer M. Harvard, Mitchell C. Sanders
  • METHODS, PEPTIDES AND BIOSENSORS USEFUL FOR DETECTING A BROAD SPECTRUM OF BACTERIA
    Publication number: 20140322790
    Abstract: Described herein are methods of detecting a wound infection and for detecting the presence or absence of bacteria, for example, wound bacteria in a sample, by contacting a sample with a peptide substrate derived from the modification of the reactive site loop (RSL) domain of the ?1-proteinase inhibitor. In the current invention, we have demonstrated that these peptide substrates without the alpha 1 protein can be efficiently used as peptide substrates. The modification or the absence of modification of this peptide substrate by the enzyme produced and/or secreted by the bacteria, can serve as an indicator for the presence or absence of the bacteria in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
    Type: Application
    Filed: December 13, 2013
    Publication date: October 30, 2014
    Applicant: WOUNDCHEK LABORATORIES
    Inventors: Shite Sebastian, Gerard J. Colpas, Diane L. Ellis-Busby, Jennifer M. Harvard, Mitchell C. Sanders