Abstract: An interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features. Also disclosed are processes of fabricating the different surface topographies, which may include separate macro processing, micro processing, and nano processing steps.

Abstract: An interbody spinal implant and a process of producing the implant. The implant includes an integration surface having a roughened surface topography as at least part of the top surface, bottom surface, or both surfaces. The integration surface comprises at least one or more of (a) a plurality of grains; (b) intergranular boundaries between the plurality of grains; and (c) unsatisfied chemical bonds. The integration surface may be produced by texturing a surface by chemical processes, mechanical processes, or both to provide the plurality of grains and intergranular boundaries and chemically etching the surface to provide unsatisfied chemical bonds. In addition, the plurality of grains and the intergranular boundaries may etch at different or non-uniform etch rates.

Abstract: A composite interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions; a first integration plate affixed to the top surface of the body; and an optional second integration plate affixed to the bottom surface of the body. At least a portion of the first integration plate, optional second integration plate, or both has a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction, inhibit migration of the implant, and promote bone growth. Also disclosed are processes of fabricating a roughened surface topography, which may include separate and sequential macro processing, micro processing, and nano processing steps.

Abstract: An interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features. Also disclosed are processes of fabricating the different surface topographies, which may include separate macro processing, micro processing, and nano processing steps.

Abstract: A composite interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions; a first integration plate affixed to the top surface of the body; and an optional second integration plate affixed to the bottom surface of the body. At least a portion of the first integration plate, optional second integration plate, or both has a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction, inhibit migration of the implant, and promote bone growth. Also disclosed are processes of fabricating a roughened surface topography, which may include separate and sequential macro processing, micro processing, and nano processing steps.

Abstract: An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and a single vertical aperture. The single vertical aperture extends from the top surface to the bottom surface, has a size and shape predetermined to maximize the surface area of the top surface and the bottom surface available proximate the anterior and posterior portions while maximizing both radiographic visualization and access to the substantially hollow center, and defines a transverse rim.

Abstract: Processes of fabricating a roughened surface topography on a composite interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions; a first integration plate affixed to the top surface of the body; and an optional second integration plate affixed to the bottom surface of the body. At least a portion of the first integration plate, optional second integration plate, or both has a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction, inhibit migration of the implant, and promote bone growth. The process steps may include separate and sequential macro processing, micro processing, and nano processing steps.

Abstract: Processes of fabricating at least one graft contact surface and other surface topographies on an interbody spinal implant, such as a solid-body or composite implant. The graft contact surface as one or more of the internal surfaces of the implant includes at least one ridge or groove, for example, which is designed to contact and promote retention and stabilization of bone growth-inducing materials placed within the internal openings of the implant body. In addition, the ridges or grooves may influence the biological processes to promote bone healing and fusion.

Abstract: Processes of fabricating different surface topographies, which may include separate macro processing, micro processing, and nano processing steps, in order to produce an interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features.

Abstract: Interbody spinal implants comprise internal sidewalls having a roughened surface topography. The internal sidewalls may be those that surround a substantially hollow implant center, including the sidewalls of a vertical aperture and sidewalls of a transverse aperture. The roughened surface topography comprises macro, micro, and nano features that comprise an amplitude, a peak to valley height, and spacing.

Abstract: An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, a single vertical aperture, and a roughened surface topography on at least the top surface. The posterior portion has a generally rounded nose profile, and has a shorter height than the anterior portion such that the spinal implant comprises a lordotic angle for aligning the spine of a patient. The junctions of the top and bottom surfaces and the anterior portion comprise a sharp edge to resist expulsion of the spinal implant upon implantation.

Abstract: An implant that has a predefined ratio of load bearing surface area to the overall size of the implant body and specifically to the surface area of a centrally located opening of a vertical aperture which connects to a center void area or passage defined by the implant body shape. This invention discloses a critical ratio or balance between loading of contained graft material through the hollow center or central passage of the implant and the implant's frictional load bearing or contact area with e.g., adjacent vertebral bones. Application of this invention to a spinal implant provides an improved integration and integration rate of the graft material or the fusion of the adjacent vertebral bone structures. The ratio between implant load bearing surface area and implant central opening area maximizes implant internal volume and allows a large passage disposed medial laterally to allow for radiographic verification of fusion growth.

Abstract: A composite interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions; a first integration plate affixed to the top surface of the body; and an optional second integration plate affixed to the bottom surface of the body. At least a portion of the first integration plate, optional second integration plate, or both has a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction, inhibit migration of the implant, and promote bone growth. Also disclosed are processes of fabricating a roughened surface topography, which may include separate and sequential macro processing, micro processing, and nano processing steps.

Abstract: An interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features. Also disclosed are processes of fabricating the different surface topographies, which may include separate macro processing, micro processing, and nano processing steps.

Abstract: An interbody spinal implant, such as a solid-body or composite implant, includes at least one graft contact surface as one or more of the internal surfaces of the implant. The graft contact surface, for example, having at least one ridge or groove is designed to contact and promote retention and stabilization of bone growth-inducing materials placed within the internal openings of the implant body. In addition, the ridges or grooves may influence the biological processes to promote bone healing and fusion. Also disclosed are processes of fabricating the graft contact surfaces and other surface topographies on the implant.

Abstract: An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, a single vertical aperture, and a roughened surface topography on at least the top surface. The posterior portion has a generally rounded nose profile, and has a shorter height than the anterior portion such that the spinal implant comprises a lordotic angle for aligning the spine of a patient. The junctions of the top and bottom surfaces and the anterior portion comprise a sharp edge to resist expulsion of the spinal implant upon implantation.

Abstract: This invention is a novel, quick release spinal implant inserter, insertion device or holder/dispenser. It has the advantage of providing enhanced surgeon control of the prosthesis insertion process including the ability to insert and manipulate intervertebral spinal fusion implants or devices of many different sizes.

Abstract: An implant that has a predefined ratio of load bearing surface area to the overall size of the implant body and specifically to the surface area of a centrally located opening of a vertical aperture which connects to a center void area or passage defined by the implant body shape. This invention discloses a critical ratio or balance between loading of contained graft material through the hollow center or central passage of the implant and the implant's frictional load bearing or contact area with e.g., adjacent vertebral bones. Application of this invention to a spinal implant provides an improved integration and integration rate of the graft material or the fusion of the adjacent vertebral bone structures. The ratio between implant load bearing surface area and implant central opening area maximizes implant internal volume and allows a large passage disposed medial laterally to allow for radiographic verification of fusion growth.

Abstract: An interbody spinal implant including a body, the body comprising: a top surface; a bottom surface; opposing lateral sides; and opposing anterior and posterior portions; the top surface, bottom surface, opposing lateral sides, internal wall surface, and opposing anterior and posterior portions defining a substantially hollow center having a single vertical aperture defining an internal wall surface, the single vertical aperture (a) extending from the top surface to the bottom surface, (b) having a size and shape predetermined to maximize the surface area of the top surface and the bottom surface available proximate the anterior and posterior portions while maximizing both radiographic visualization and access to the substantially hollow center, and (c) defining a transverse rim, wherein at least a portion of the internal wall surface has a roughened surface topography.

Abstract: A polyester blend composition that comprises at least two copolymers selected from certain copolymers, particularly blends of branched and linear biodegradable copolymers. Also provided is a blown film that is produced from the polyester blend composition, and a process for producing the polyester blend composition and the film. The film is biodegradable, transparent, and has excellent mechanical properties.