Patents by Inventor Jennifer McLarnan

Jennifer McLarnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Random transposon insertion in and use thereof to identify essential genes
    Patent number: 8173363
    Abstract: The invention provides a method for generating a database of candidate essential genes in Staphylococcus aureus, as well as otherwise important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing S. aureus infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing Staphylococcus infection.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: May 8, 2012
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Kim Folger Bruce, Paul Warrener, Jennifer McLarnan, Kevin Hou
  • Random transposon insertion in staphylococcus aureus and use thereof to identify essential genes
    Publication number: 20060234233
    Abstract: The invention provides a method for generating a database of candidate essential genes in Staphylococcus aureus, as well as otherwise important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing S. aureus infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing Staphylococcus infection.
    Type: Application
    Filed: August 20, 2003
    Publication date: October 19, 2006
    Applicant: CHIRON CORPORATION
    Inventors: Kim Bruce, Paul Warrener, Jennifer McLarnan, Kevin Hou