Abstract: Preferred aspects of the present invention relate to a device for filtration comprising at least one rotor configured to create Taylor vortices on at least one side of a filtration membrane, thereby providing substantially enhanced mass or heat transfer across the membrane.

Abstract: The present invention relates to a system for two-stage blood dialysis of a patient. In one embodiment, the system comprises a first filtration device for receiving the blood from the patient and for producing a first filtrate and processed blood. The system further comprises a second filtration device for receiving the first filtrate and producing replacement fluid and waste product. At least one of the first and second filtration devices preferably comprises a Taylor vortex-enhanced blood filtration device.