Patents by Inventor Jennifer O'Hara Lauchle

Jennifer O'Hara Lauchle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of breast cancer using combination therapies comprising GDC-9545 and a CDK4/6 inhibitor
    Patent number: 11918561
    Abstract: Provided herein are combination therapies comprising GDC-9545 and a CDK4/6 inhibitor for treating locally advanced breast cancer or metastatic breast cancer.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: March 5, 2024
    Assignee: Genentech, Inc.
    Inventors: Jennifer O'Hara Lauchle, Sandra Milan, Melanie Carol Smitt, Marjorie C. Green
  • COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER
    Publication number: 20230088701
    Abstract: Provided are combination therapies comprising a PI3K inhibitor (e.g., inavolisib), a CDK4/6 inhibitor (e.g., palbociclib), and fulvestrant; and methods of treating hormone receptor positive and HER2 negative (HR+/HER2?) locally advanced or metastatic breast cancer in a patient (preferably a patient with a PIC3CA mutant patient) comprising administering a therapeutically effective amount of inavolisib, or a pharmaceutically acceptable salt thereof, a CDK4/6 inhibitor (e.g., palbociclib), and fulvestrant or letrozole.
    Type: Application
    Filed: June 3, 2022
    Publication date: March 23, 2023
    Applicant: Genentech, Inc.
    Inventors: Jennifer O'Hara Lauchle, Michael Joseph Mamounas, Jennifer Lee Schutzman, Lori Sickels Friedman, Jian Huang
  • TREATMENT OF BREAST CANCER USING COMBINATION THERAPIES COMPRISING GDC-9545 AND A CDK4/6 INHIBITOR
    Publication number: 20210353601
    Abstract: Provided herein are combination therapies comprising GDC-9545 and a CDK4/6 inhibitor for treating locally advanced breast cancer or metastatic breast cancer.
    Type: Application
    Filed: May 10, 2021
    Publication date: November 18, 2021
    Applicant: Genentech, Inc.
    Inventors: Jennifer O'Hara LAUCHLE, Sandra MILAN, Melanie Carol SMITT, Marjorie C. GREEN
  • METHODS OF TREATING MESOTHELIOMA WITH A PI3K INHIBITOR COMPOUND
    Publication number: 20120308562
    Abstract: Methods are provided for treating mesothelioma patients with a dual PI3K/mTOR inhibitor, GDC-0980: (S)-1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one, and having the structure:
    Type: Application
    Filed: June 1, 2012
    Publication date: December 6, 2012
    Inventors: Mika K. Derynck, Jennifer O'Hara Lauchle