Abstract: Provided herein are methods of treating multiple myeloma, comprising administering to a subject with multiple myeloma an inhibitor of Nuclear Receptor Binding SET Domain Protein 2 (NSD2). Also provided are methods of use wherein the multiple myeloma has previously been determined to have a 4:14 chromosome translocation (t(4;14)).

Abstract: Provided are microfluidic chip-based models of immune system tissues. In some embodiments, the models include a microfluidic housing having a cell culture chamber and one or more channels in communication with the cell culture chamber and a cell culture residing in the cell culture chamber, wherein the cell culture includes one or more cells of the immune system. Also provided are systems that include one or more microfluidic chip-based models of immune system tissues, methods for patterning cells in culture on microfluidic chips, and methods for modeling immune responses of subjects using the same.

Abstract: A convertible garment may be constructed from a material having a bulk section between opposing ends. The material may substantially encircle bands located at the opposing ends. Bundling strings may encircle the material near the ends with an adjustable and independent level of compactness. Additionally, connecting strings may be attached to the material at the ends for positioning the opposing ends of the material adjacent to one another. Compactness of the majority of the material in the bulk section may be adjustable relative to a desired coverage of a wearer. The material may be hemmed. Stitching may be included near the ends to supplement the bundling strips. The material may be a textile that is adjustable to cover a length of the wearer up to between shoulders and hips of the wearer. A method of using the convertible garment is also disclosed.

Abstract: A convertible garment may be constructed from a material having a bulk section between opposing ends. The material may substantially encircle bands located at the opposing ends. Bundling strings may encircle the material near the ends with an adjustable and independent level of compactness. Additionally, connecting strings may be attached to the material at the ends for positioning the opposing ends of the material adjacent to one another. Compactness of the majority of the material in the bulk section may be adjustable relative to a desired coverage of a wearer. The material may be hemmed. Stitching may be included near the ends to supplement the bundling strips. The material may be a textile that is adjustable to cover a length of the wearer up to between shoulders and hips of the wearer. A method of using the convertible garment is also disclosed.

Abstract: A convertible garment may be constructed from a material having a bulk section between opposing ends. Bundling strings may encircle the material near the ends with an adjustable and independent level of compactness. Additionally, connecting strings may be attached to the material at the ends for positioning the opposing ends of the material adjacent to one another. Compactness of the majority of the material in the bulk section may be adjustable relative to a desired coverage of a wearer. The material may be hemmed. Stitching may be included near the ends to supplement the bundling strips. The material may be a textile that is adjustable to cover a length of the wearer up to between shoulders and hips of the wearer. A method of using the convertible garment is also disclosed.