Patents by Inventor Jennifer Qiao

Jennifer Qiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-LINKED HETEROCYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS
    Publication number: 20100197716
    Abstract: The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
    Type: Application
    Filed: April 16, 2010
    Publication date: August 5, 2010
    Inventors: Jennifer Qiao, Tammy C. Wang, James C. Sutton, Timur Gungor
  • N-linked heterocyclic antagonists of P2Yreceptor useful in the treatment of thrombotic conditions
    Patent number: 7728008
    Abstract: The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: June 1, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer Qiao, Tammy C. Wang, James C. Sutton, Timur Gungor
  • LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
    Publication number: 20080090807
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: December 13, 2007
    Publication date: April 17, 2008
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • HETEROCYCLIC CETP INHIBITORS
    Publication number: 20070161685
    Abstract: Compounds of formula Ia and Ib wherein A, B, C and R1 are described herein.
    Type: Application
    Filed: November 15, 2006
    Publication date: July 12, 2007
    Inventors: Mark Salvati, Heather Finlay, Lalgudi Harikrishnan, Ji Jiang, James Johnson, Muthoni Kamau, R. Lawrence, Michael Miller, Jennifer Qiao, Tammy Wang, Yufeng Wang, Wu Yang
  • LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS
    Publication number: 20070135428
    Abstract: The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: P4-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: February 16, 2007
    Publication date: June 14, 2007
    Inventors: Jennifer Qiao, Tammy Wang, Gren Wang, Timur Gungor
  • HETEROCYCLIC CETP INHIBITORS
    Publication number: 20070135631
    Abstract: Compounds of formula Ia and Ib wherein A, B, C and R1 are described herein.
    Type: Application
    Filed: November 13, 2006
    Publication date: June 14, 2007
    Inventors: Mark Salvati, Heather Finlay, Bang-Chi Chen, Lalgudi Harikrishnan, Ji Jiang, James Johnson, Muthoni Kamau, R. Lawrence, Jianqing Li, John Lloyd, Michael Miller, Zulan Pi, Jennifer Qiao, Richard Rampulla, Jacques Roberge, Tammy Wang, Yufeng Wang, Wu Yang
  • LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
    Publication number: 20070135426
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: January 16, 2007
    Publication date: June 14, 2007
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • LACTAM-CONTAINING DIAMINOALKYL, Beta-AMINOACIDS, Alpha-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
    Publication number: 20070129361
    Abstract: The present application describes lactam-containing diaminoalkyl, ?-aminoacids, ?-aminoacids and derivatives thereof of Formula I: P-M-M1??I or pharmaceutically acceptable salt forms thereof, wherein M is a linear core. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: January 12, 2007
    Publication date: June 7, 2007
    Inventors: Jennifer Qiao, Wei Han
  • N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
    Publication number: 20060293281
    Abstract: The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
    Type: Application
    Filed: June 26, 2006
    Publication date: December 28, 2006
    Applicant: Bristol-Myers Squibb Company
    Inventors: Jennifer Qiao, Tammy Wang, James Sutton, Timur Gungor
  • C-linked cyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
    Publication number: 20060293336
    Abstract: The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
    Type: Application
    Filed: June 26, 2006
    Publication date: December 28, 2006
    Applicant: Bristol-Myers Squibb Company
    Inventors: James Sutton, Jennifer Qiao, Carl Thibeault, Rejean Ruel
  • Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
    Publication number: 20060247243
    Abstract: The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: June 21, 2006
    Publication date: November 2, 2006
    Inventors: Joanne Smallheer, Donald Pinto, Shuaige Wang, Jennifer Qiao, Wei Han, Zilun Hu
  • Glycinamides as factor Xa inhibitors
    Patent number: 7115627
    Abstract: The present application describes glycinamidic compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: October 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Donald J. P. Pinto, Wei Han, Zilun Hu, Jennifer Qiao
  • Lactam-containing compounds and derivatives thereof as factor xa inhibitors
    Publication number: 20050267097
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: August 5, 2005
    Publication date: December 1, 2005
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
    Publication number: 20050267119
    Abstract: The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.
    Type: Application
    Filed: May 11, 2005
    Publication date: December 1, 2005
    Inventors: Hannguang Chao, Huji Tuerdi, Timothy Herpin, Jacques Roberge, Yalei Liu, R. Lawrence, Robert Rehfuss, Charles Clark, Jennifer Qiao, Timur Gungor, Patrick Lam, Tammy Wang, Rejean Ruel, Alexandre L'Heureux, Carl Thibeault, Gilles Bouthillier, Dora Schnur
  • Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
    Publication number: 20050261244
    Abstract: The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.
    Type: Application
    Filed: May 10, 2005
    Publication date: November 24, 2005
    Inventors: Huji Tuerdi, Hannguang Chao, Jennifer Qiao, Tammy Wang, Timur Gungor
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Publication number: 20050261287
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4 ??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: June 16, 2005
    Publication date: November 24, 2005
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors
    Patent number: 6951872
    Abstract: The present application describes monocyclic or bicyclic carbocycles and heterocycles and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: October 4, 2005
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Irina C. Jacobson, Ruth R. Wexler, Suanne Nakajima, Mimi L. Quan, Shuaige Wang, Joanne M. Smallheer, Jennifer Qiao
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Publication number: 20050171085
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: October 21, 2004
    Publication date: August 4, 2005
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Publication number: 20050124602
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: October 20, 2004
    Publication date: June 9, 2005
    Inventors: Donald Pinto, Mimi Quan, Michael Orwat, Yun-Long Li, Wei Han, Jennifer Qiao, Patrick Lam, Stephanie Koch
  • Monocyclic and bicyclic lactams as factor Xa inhibitors
    Publication number: 20050107361
    Abstract: The present application describes monocyclic and bicyclic lactams and derivatives thereof of Formulae Ia-e: wherein one of one of T1 and T2 is carbonyl, thiocarbonyl, or sulfonyl or pharmaceutically acceptable salt forms thereof. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Application
    Filed: September 28, 2004
    Publication date: May 19, 2005
    Inventors: Wei Han, Jennifer Qiao, Zilun Hu