Abstract: A compressive patient warming device is provided. The device includes an elastic inner layer that conforms snugly to a shape of an appendage of a patient so that the inner layer wraps around and substantially contacts most of an underlying surface area of the appendage. An outer layer is attached to and covers the inner layer to form a space that holds a heat transfer medium between the inner layer and the outer layer while the inner layer is wrapped around the appendage. The outer layer may be a rigid layer, and a predetermined compressive load may be applied to the outer layer to encourage blood flow in the appendage. A source of heat may be applied to the device to maintain normothermia and/or treat hypothermia.

Abstract: A compressive patient warming device is provided. The device includes an elastic inner layer that conforms snugly to a shape of an appendage of a patient so that the inner layer wraps around and substantially contacts most of an underlying surface area of the appendage. An outer layer is attached to and covers the inner layer to form a space that holds a heat transfer medium between the inner layer and the outer layer while the inner layer is wrapped around the appendage. The outer layer may be a rigid layer, and a predetermined compressive load may be applied to the outer layer to encourage blood flow in the appendage. A source of heat may be applied to the device to maintain normothermia and/or treat hypothermia.

Abstract: A compressive patient warming device is provided. The device includes an elastic inner layer that conforms snugly to a shape of an appendage of a patient so that the inner layer wraps around and substantially contacts most of an underlying surface area of the appendage. An outer layer is attached to and covers the inner layer to form a space that holds a heat transfer medium between the inner layer and the outer layer while the inner layer is wrapped around the appendage. The outer layer may be a rigid layer, and a predetermined compressive load may be applied to the outer layer to encourage blood flow in the appendage. A source of heat may be applied to the device to maintain normothermia and/or treat hypothermia.

Abstract: The present invention relates generally to antimicrobial hydrogel polymers, and dressings comprising one or more hydrogel-forming hydrophilic polymers, where the hydrogels and dressings further comprise one or more antimicrobial agents that are released from the hydrogel in a controlled manner. The hydrogels and dressings may be used for medical, veterinary, and/or cosmetic applications. The dressings may be applied, for example, as wound dressings, surgical dressings, and percutaneous site dressings. In certain aspects of the invention, the dressings may be beneficially used in methods of accelerating wound healing, preventing and/or reducing the incidence of wound infection, and reducing scarring associated with wounds.

Abstract: A sterilized medical device comprising minocycline and rifampin is described. The device is setrerilized by e-beam raditation such that degradation of minocycline and rifampin is minimized. Methods for sterilizing minocycline and rifampin-containing devices by e-beam radiation and methods of manufacturing devices, which methods include e-beam sterilization, are also described.

Abstract: A bioresorbable and hemostatic plug for embolization made from a collagen piece is compressed so as to be longitudinally insertable into a tubular biological vessel such as a blood vessel to be occluded. The collagen piece is capable of expanding radially inside the vessel by absorbing fluid such as the blood and thereby providing mechanical fixation in and occlusion of the vessel. Two such collagen pieces may be used with a spacer of a different material in between. Different kinds of therapeutic agents can be bonded to or physically absorbed by the collagen pieces so as to be delivered to the site of occlusion.